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首页> 美国卫生研究院文献>Scientific Reports >Prognostic values of red blood cell distribution width platelet count and red cell distribution width-to-platelet ratio for severe burn injury
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Prognostic values of red blood cell distribution width platelet count and red cell distribution width-to-platelet ratio for severe burn injury

机译：红细胞分布宽度血小板计数和红细胞分布宽度与血小板比率对严重烧伤的预后价值

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摘要

Red blood cell distribution width (RDW), platelet count (PLT), and a RDW-to-PLT ratio (RPR) have been associated with inflammatory activity and adverse outcomes in many diseases. This study has aimed to investigate the association between these indicators and the mortality rate of severe burn patients. From 2008 to 2014, 610 cases of severe burn patients from two burn centers in eastern China were enrolled in this study. Eighty-eight patients died within 90 days after admission. The RDW, PLT, and RPR were studied through Cox regression analysis on the 3rd and 7th day. The RDW, PLT, and RPR values on the 3rd and 7th day were significantly associated with the outcomes of severe burn patients (P < 0.01). High RPR was significantly associated with a 90-day mortality rate at the two time points. However, the RDW and PLT did not provide independent predictive values. Our results indicated that the RPR values on the 3rd and 7th day were associated with the mortality rates of severe burn patients (P < 0.01). Meanwhile, the RDW and PLT values at these time points failed to provide independent values for burn mortality prediction. Thus, the RPR can serve as an independent and novel marker for mortality rates prediction in severe burn patients.
机译：在许多疾病中，红细胞分布宽度（RDW），血小板计数（PLT）和RDW与PLT之比（RPR）与炎症活动和不良后果相关。这项研究旨在调查这些指标与严重烧伤患者死亡率之间的关系。 2008年至2014年，本研究纳入了来自中国东部两个烧伤中心的610例严重烧伤患者。入院后90天内有88名患者死亡。在第3天和第7天通过Cox回归分析研究RDW，PLT和RPR。第3天和第7天的RDW，PLT和RPR值与严重烧伤患者的结局显着相关（P <0.01）。高RPR与两个时间点的90天死亡率显着相关。但是，RDW和PLT没有提供独立的预测值。我们的结果表明，第3天和第7天的RPR值与严重烧伤患者的死亡率相关（P <0.01）。同时，在这些时间点的RDW和PLT值未能为烧伤死亡率预测提供独立的值。因此，RPR可作为严重烧伤患者死亡率预测的独立且新颖的标记。

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