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首页> 美国卫生研究院文献>The Journal of International Medical Research >Rescue of four pediatric patients with severe influenza A (H3N2) in Weifang China
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Rescue of four pediatric patients with severe influenza A (H3N2) in Weifang China

机译：潍坊市4例重症甲型H3N2儿科患者的抢救

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In this report, we summarize our experience of rescuing four children with severe type A H3N2 influenza from January to February 2017 in Weifang People’s Hospital, Shandong Province, China for reference in clinical treatment. Two boys and two girls, ranging in age from 3 months to 6 years, with fever, cough, and asthma, were admitted to the pediatric intensive care unit. All children had severe pulmonary infection with respiratory distress. Three children had myocardial damage, two had liver damage, and one had encephalitis. One child had a history of bronchial asthma and one had severe spinal muscular atrophy. After all four children were admitted to the pediatric intensive care unit, they were provided active and effective organ function support and ventilator-assisted respiration. They were treated with gamma globulin, methylprednisolone, and antibiotics. Three children were treated with anti-influenza drugs and recovered from influenza; one child died even before antiviral treatment intervention on the first day. Definite diagnosis of the cases was through clinical manifestations, supplemented by laboratory tests, such as influenza virus H3N2 rapid antigen detection and nucleic acid detection. Early antiviral therapy, high-dose glucocorticoids and immunoglobulins, and systemic comprehensive rescue might be important for rescuing children with severe influenza A (H3N2).
机译：在本报告中，我们总结了我们于2017年1月至2月在中国山东省潍坊市人民医院救出4名重度A型H3N2流感儿童的经验，以供临床治疗参考。小儿重症监护病房收治了两个男孩和两个女孩，年龄在3个月至6岁之间，伴有发烧，咳嗽和哮喘。所有儿童均患有严重的肺部感染并伴有呼吸窘迫。三个孩子有心肌损伤，两个孩子有肝损伤，其中一个有脑炎。一个孩子有支气管哮喘病史，一个孩子患有严重的脊髓性肌萎缩。在所有四个孩子都被送入小儿重症监护室后，他们将获得积极有效的器官功能支持和呼吸机辅助呼吸。他们接受了丙种球蛋白，甲基泼尼松龙和抗生素治疗。 3名儿童接受了抗流感药物治疗并从流感中康复；甚至在第一天未进行抗病毒治疗之前就有一个孩子死亡。病例的确诊是通过临床表现，辅之以实验室检测，例如流感病毒H3N2快速抗原检测和核酸检测。早期抗病毒治疗，大剂量糖皮质激素和免疫球蛋白以及全身全面抢救对于抢救患有严重A型流感（H3N2）的儿童可能很重要。

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