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A new look at the essence of the imaging photoplethysmography

机译:影像光体积描记术本质的新视角

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摘要

Photoplethysmography (PPG) is a noninvasive optical method accepted in the clinical use for measurements of arterial oxygen saturation. It is widely believed that the light intensity after interaction with the biological tissue in vivo is modulated at the heartbeat frequency mainly due to pulsatile variations of the light absorption caused by arterial blood-volume pulsations. Here we report experimental observations, which are not consistent with this model and demonstrate the importance of elastic deformations of the capillary bed in the formation of the PPG waveform. These results provide new insight on light interaction with live tissue. To explain the observations we propose a new model of PPG in which pulse oscillations of the arterial transmural pressure deform the connective-tissue components of the dermis resulting in periodical changes of both the light scattering and absorption. These local changes of the light-interaction parameters are detected as variations of the light intensity returned to a photosensitive camera. Therefore, arterial pulsations can be indirectly monitored even by using the light, which slightly penetrates into the biological tissue.
机译:光电容积描记术(PPG)是一种在临床中用于测量动脉血氧饱和度的非侵入性光学方法。普遍认为,在体内与生物组织相互作用之后的光强度在心跳频率上被调节,这主要是由于动脉血容量脉动引起的光吸收的脉动变化。在这里我们报告实验观察,这与该模型不一致,并证明了在PPG波形的形成中毛细管床的弹性变形的重要性。这些结果为光与活组织的相互作用提供了新的见解。为了解释这些观察结果,我们提出了一种新的PPG模型,其中动脉透壁压力的脉冲振荡使真皮的结缔组织成分变形,从而导致光散射和吸收的周期性变化。这些光相互作用参数的局部变化被检测为返回到光敏相机的光强度的变化。因此,即使使用略微穿透生物组织的光,也可以间接地监测动脉搏动。

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