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The Dynamic Dielectric at a Brain Functional Site and an EM Wave Approach to Functional Brain Imaging

机译:脑功能部位的动态介电体和电磁波方法进行功能性脑成像

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摘要

Functional brain imaging has tremendous applications. The existing methods for functional brain imaging include functional Magnetic Resonant Imaging (fMRI), scalp electroencephalography (EEG), implanted EEG, magnetoencephalography (MEG) and Positron Emission Tomography (PET), which have been widely and successfully applied to various brain imaging studies. To develop a new method for functional brain imaging, here we show that the dielectric at a brain functional site has a dynamic nature, varying with local neuronal activation as the permittivity of the dielectric varies with the ion concentration of the extracellular fluid surrounding neurons in activation. Therefore, the neuronal activation can be sensed by a radiofrequency (RF) electromagnetic (EM) wave propagating through the site as the phase change of the EM wave varies with the permittivity. Such a dynamic nature of the dielectric at a brain functional site provides the basis for an RF EM wave approach to detecting and imaging neuronal activation at brain functional sites, leading to an RF EM wave approach to functional brain imaging.
机译:功能性脑成像具有巨大的应用。用于功能性脑成像的现有方法包括功能性磁共振成像(fMRI),头皮脑电图(EEG),植入式脑电图,磁脑图(MEG)和正电子发射断层扫描(PET),这些方法已广泛且成功地应用于各种脑成像研究。要开发一种用于大脑功能成像的新方法,这里我们显示大脑功能部位的电介质具有动态性质,随局部神经元激活而变化,因为电介质的介电常数随激活时周围神经元周围细胞外液的离子浓度而变化。因此,当EM波的相位变化随介电常数变化时,可以通过在该部位传播的射频(RF)电磁(EM)波来感知神经元的激活。大脑功能部位电介质的这种动态特性为RF EM波方法提供了基础,该方法用于检测和成像大脑功能部位的神经元激活,从而导致RF EM波方法实现功能性大脑成像。

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