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首页> 美国卫生研究院文献>Journal of Korean Medical Science >The validity of the ISAAC written questionnaire and the ISAAC video questionnaire (AVQ 3.0) for predicting asthma associated with bronchial hyperreactivity in a group of 13-14 year old Korean schoolchildren.
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The validity of the ISAAC written questionnaire and the ISAAC video questionnaire (AVQ 3.0) for predicting asthma associated with bronchial hyperreactivity in a group of 13-14 year old Korean schoolchildren.

机译：ISAAC书面问卷和ISAAC视频问卷（AVQ 3.0）在预测13-14岁韩国小学生哮喘与支气管高反应性相关的哮喘中的有效性。

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To validate the prevalence rate of symptoms of asthma produced by the phase I ISAAC (International Study of Asthma and Allergies in Childhood) study, hypertonic saline challenge test was carried out during the phase II study at a year after the phase I study. For the phase II study, six middle schools from three cities in the phase I study were selected. Finally, 499 children who responded to both studies were analyzed. All subjects were asked to complete the written questionnaire (WQ) first, followed by a video questionnaire (AVQ 3.0) during the phase I study. Of the 499 children, only 19 (3.8%) were positive to the hypertonic saline bronchial challenge test. The degree of agreement between responses to the two corresponding questions "wheezing at rest" and "nocturnal wheeze" in the AVQ 3.0 and WQ were moderate and weak with a Kappa indices of 0.45 and 0.23, respectively. The question on "severe wheeze" in the AVQ 3.0 had the highest Youden's index among the five questions related to asthma symptoms in the previous 12 months, but its specificity was low whereas its sensitivity was 1.0. There was no consistency of priority between the two questionnaires in predicting bronchial hyperreactivity in a group of Korean schoolchildren. Therefore we need to develop more appropriate WQ or AVQ to compare the prevalences of asthma to other countries.
机译：为了验证I阶段ISAAC（儿童哮喘和过敏国际研究）研究产生的哮喘症状的患病率，在I阶段研究后一年的II阶段研究中进行了高渗盐溶液刺激试验。对于第二阶段的研究，选择了第一阶段研究的三个城市的六所中学。最后，分析了对这两项研究均有效的499名儿童。在第一阶段研究期间，要求所有受试者先完成书面问卷（WQ），然后完成视频问卷（AVQ 3.0）。在499名儿童中，只有19名（3.8％）对高渗盐水支气管激发试验呈阳性。在AVQ 3.0和WQ中，对两个相应问题“喘息着”和“夜间喘息”的回答之间的一致程度是中度和弱度，Kappa指数分别为0.45和0.23。在过去12个月中，与哮喘症状相关的五个问题中，AVQ 3.0中的“重度喘息”问题具有最高的尤登指数，但其特异性较低，而敏感性为1.0。在预测一组韩国学龄儿童的支气管反应过度时，两个问卷之间的优先级不一致。因此，我们需要开发更合适的WQ或AVQ来比较其他国家的哮喘患病率。

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