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首页> 美国卫生研究院文献>Journal of Womens Health >The Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium: A Transdisciplinary Approach Toward Promoting Bladder Health and Preventing Lower Urinary Tract Symptoms in Women Across the Life Course
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The Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium: A Transdisciplinary Approach Toward Promoting Bladder Health and Preventing Lower Urinary Tract Symptoms in Women Across the Life Course

机译：预防下泌尿道症状（PLUS）研究联盟：跨学科方法旨在促进一生中妇女的膀胱健康和预防下泌尿道症状

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摘要

Lower urinary tract symptoms (LUTS) are highly prevalent in women, and are expected to impose a growing burden to individuals and society as the population ages. The predominance of research related to LUTS has focused on underlying pathology, disease mechanisms, or the efficacy of treatments for women with LUTS. Although this research has been vital for helping to reduce or ameliorate LUTS conditions, it has done little to prevent the onset of LUTS. Health promotion and prevention require an expansion of scientific inquiry beyond the traditional paradigm of studying disease mechanisms and treatment to the creation of an evidence base to support recommendations for bladder health promotion and, in turn, prevention of LUTS. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) introduced the concept of prevention as an important priority for women's urologic research as a prelude to supporting the formation of the Prevention of Lower Urinary Tract Symptoms (PLUS) research consortium. In this article, we introduce the PLUS research consortium to the scientific community; share the innovative paradigms by which the consortium operates; and describe its unique research mission: to identify factors that promote bladder health across the life course and prevent the onset of LUTS in girls and women.
机译：下尿路症状（LUTS）在女性中非常普遍，并且随着人口的老龄化，预计会给个人和社会带来越来越大的负担。与LUTS相关的研究主要集中在对LUTS妇女的潜在病理学，疾病机制或治疗功效上。尽管这项研究对于帮助减轻或改善LUTS病情至关重要，但对于预防LUTS的发作却无济于事。促进健康和预防健康需要将科学研究扩展到传统的研究疾病机制和治疗范式之外，以建立证据基础来支持有关促进膀胱健康以及预防LUTS的建议。国立糖尿病，消化与肾病研究所（NIDDK）将预防的概念作为妇女泌尿科研究的重要优先事项，介绍了支持成立预防下尿路症状（PLUS）研究联盟的前奏。在本文中，我们向科学界介绍了PLUS研究联盟；分享财团运作的创新范例；并描述其独特的研究任务：确定在整个生命过程中促进膀胱健康并防止女孩和妇女发生LUTS的因素。

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