• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>Journal of Korean Medical Science >The Effectiveness of Recombinant Human Thyroid-Stimulating Hormone versus Thyroid Hormone Withdrawal Prior to Radioiodine Remnant Ablation in Thyroid Cancer: A Meta-Analysis of Randomized Controlled Trials
【2h】

The Effectiveness of Recombinant Human Thyroid-Stimulating Hormone versus Thyroid Hormone Withdrawal Prior to Radioiodine Remnant Ablation in Thyroid Cancer: A Meta-Analysis of Randomized Controlled Trials

机译：甲状腺癌中放射性碘残留消融前重组人促甲状腺激素与撤回甲状腺激素的有效性：一项随机对照试验的荟萃分析

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We evaluated the efficacy of recombinant human thyroid-stimulating hormone (rhTSH) versus thyroid hormone withdrawal (THW) prior to radioiodine remnant ablation (RRA) in thyroid cancer. A systematic search of MEDLINE, EMBASE, the Cochrane Library, and SCOPUS was performed. Randomized controlled trials that compared ablation success between rhTSH and THW at 6 to 12 months following RRA were included in this study. Six trials with a total of 1,660 patients were included. When ablation success was defined as a thyroglobulin (Tg) cutoff of 1 ng/mL (risk ratio, 0.99; 95% confidence interval, 0.96-1.03) or a Tg cutoff of 1 ng/mL plus imaging modality (RR 0.97; 0.90-1.05), the results of rhTSH and THW were similar. There were no significant differences when ablation success was defined as a Tg cutoff of 2 ng/mL (RR 1.03; 0.95-1.11) or a Tg cutoff of 2 ng/mL plus imaging modality (RR 1.02; 0.95-1.09). When a negative 131I-whole body scan was used solely as the definition of ablation success, the effects of rhTSH and THW were not significantly different (RR 0.97; 0.93-1.02). Therefore, ablation success rates are comparable when RRA is prepared by either rhTSH or THW.
机译：我们评估了在甲状腺癌中进行放射性碘残留消融（RRA）之前，重组人促甲状腺激素（rhTSH）与甲状腺激素戒断（THW）的疗效。对MEDLINE，EMBASE，Cochrane库和SCOPUS进行了系统搜索。这项研究包括随机对照试验，比较了RRA后6到12个月rhTSH和THW之间的消融成功率。包括总共1,660名患者的六项试验。消融成功定义为甲状腺球蛋白（Tg）截止值为1 ng / mL（风险比为0.99； 95％置信区间为0.96-1.03）或Tg截止值为1 ng / mL加上成像方式（RR 0.97； 0.90- 1.05），rhTSH和THW的结果相似。将消融成功定义为2 ng / mL的Tg截止值（RR 1.03; 0.95-1.11）或2 ng / mL的Tg截止值加上成像方式（RR 1.02; 0.95-1.09）时，没有显着差异。当消极的 131 I全身扫描仅用作消融成功的定义时，rhTSH和THW的影响没有显着差异（RR 0.97； 0.93-1.02）。因此，当通过rhTSH或THW制备RRA时，消融成功率是可比的。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号