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Comprehensive assessment of cryogenic storage risk and quality management concerns: best practice guidelines for ART labs

机译:低温储存风险和质量管理问题的综合评估:ART实验室的最佳实践指南

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摘要

Recent publicized events of cryogenic storage tank failures have created nationwide concern among infertility patients and patients storing embryos and gametes for future use. To assure patient confidence, quality management (QM) plans applied by in vitro fertilization (IVF) laboratories need to include a more comprehensive focus on the cryostorage of reproductive specimens. The purpose of this review is to provide best practice guidelines for the cryogenic storage of sperm, oocytes, embryos, and other reproductive tissues (e.g., testicular and ovarian tissue, cord blood cells, and stem cells) and recommend a strategy of thorough and appropriate quality and risk management procedures aimed to alleviate or minimize the consequences from catastrophic events.
机译:最近公开的低温储罐故障事件已引起全国范围内对不育症患者以及储存胚胎和配子以备将来使用的患者的关注。为了确保患者的信心,体外受精(IVF)实验室实施的质量管理(QM)计划需要更加全面地关注生殖标本的冷冻保存。这篇综述的目的是为精子,卵母细胞,胚胎和其他生殖组织(例如,睾丸和卵巢组织,脐带血细胞和干细胞)的低温储存提供最佳实践指南,并建议彻底和适当的策略质量和风险管理程序旨在减轻或减少灾难性事件的后果。

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