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首页> 美国卫生研究院文献>Journal of Lasers in Medical Sciences >Effect of Nonsurgical Periodontal Treatment Combined With Diode Laser or Photodynamic Therapy on Chronic Periodontitis: A Randomized Controlled Split-Mouth Clinical Trial
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Effect of Nonsurgical Periodontal Treatment Combined With Diode Laser or Photodynamic Therapy on Chronic Periodontitis: A Randomized Controlled Split-Mouth Clinical Trial

机译：非手术性牙周治疗联合二极管激光或光动力疗法对慢性牙周炎的影响：一项随机对照的分口临床试验

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>Introduction: The optimum removal of bacteria and their toxins from periodontal pockets is not always obtained by conventional mechanical debridement. Adjunctive therapies may improve tissue healing through detoxification and bactericidal effects. The purpose of the present study was to evaluate the impact of adjunctive laser therapy (LT) and photodynamic therapy (PDT) on patients with chronic periodontitis. >Methods: Twenty patients with at least three quadrants involved and each of them presenting pockets 4-8 mm deep were included in the study. Periodontal treatment comprising scaling and root planning (SRP) was accomplished for the whole mouth. Applying a split-mouth design, each quadrant was randomly treated with SRP alone (group A), SRP with LT (group B), and SRP with PDT (group C). The clinical indices were measured at baseline 6 weeks and 3 months after treatment. Microbiological samples were taken and evaluated at baseline and 3-month follow-up. >Results: All groups showed statistically significant improvements in terms of clinical attachment level (CAL) gain, periodontal pocket depth (PPD) reduction, papilla bleeding index and microbial count compared to baseline (P < .05). The results showed more significant improvement in the 6-week evaluation in terms of CAL in groups B and C than in group A (P < .05). Group B also revealed a greater reduction in PPD than the other treatment modalities (P < .05). >Conclusion: The obtained data suggested that adjunctive LT and PDT have significant short-term benefits in the treatment of chronic periodontitis. Furthermore, LT showed minimal additional advantages compared to PDT.
机译：>简介：通过常规机械清创术并不总是能够最佳地去除牙周袋中的细菌及其毒素。辅助疗法可通过排毒和杀菌作用改善组织愈合。本研究的目的是评估辅助激光疗法（LT）和光动力疗法（PDT）对慢性牙周炎患者的影响。 >方法：该研究纳入了20名患者，涉及至少三个象限，每个象素深4-8 mm。整个口腔均完成了包括洗牙和牙根计划（SRP）在内的牙周治疗。应用裂口设计，每个象限随机接受单独SRP治疗（A组），SRP LT治疗（B组）和SRP和PDT治疗（C组）。在治疗后6周和3个月的基线测量临床指数。在基线和3个月的随访中采集微生物样品并进行评估。 >结果：与基线相比，所有组的临床依从水平（CAL）增高，牙周袋深度（PPD）减少，乳头出血指数和微生物计数方面均具有统计学上的显着改善（P <.05）。结果表明，在B组和C组的CAL方面，为期6周的评估比A组有显着改善（P <.05）。与其他治疗方式相比，B组还显示PPD降低更大（P <.05）。 >结论：获得的数据表明，LT和PDT辅助治疗慢性牙周炎具有明显的短期益处。此外，与PDT相比，LT显示出最小的附加优势。

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