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Therapeutic significance and pharmacological activities of antidiarrheal medicinal plants mention in Ayurveda: A review

机译:阿育吠陀中提到的止泻药用植物的治疗意义和药理活性:综述

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摘要

Diarrhea is a serious problem affecting 3-5 billion people per year around the world, especially children of below 5 years. 70% of the world population uses traditional and indigenous medicine for their primary health care. The facts of these indigenous remedies are passed verbally and sometimes as documents. Since ancient time, Ayurveda is the main system of healing in South East Asian countries. Indian literature from ayurvedic texts and other books claim the potency of several plants in the treatment of diarrhea. As the global prospective of ayurvedic medicine is increasing, interest regarding the scientific basis of their action is parallely increasing. Researchers are doing experiments to establish the relation between the claimed action and observed pharmacological activities. In the present article, an attempt was made to compile the scientific basis of medicinal plants used to cure diarrhea in Ayurveda. Literature was collected via electronic search (PubMed, ScienceDirect, Medline, and Google Scholar) from published articles that reports antidiarrheal activity of plants that were mentioned in Ayurveda classics. A total of 109 plant species belonging to 58 families were reported for their antidiarrheal activity. Several Indian medicinal plants have demonstrated promising antidiarrheal effects, but the studies on the antidiarrheal potentials of these plants are not taken beyond proof of concept stage. It is hoped that the article would stimulate future clinical studies because of the paucity of knowledge in this area.
机译:腹泻是一个严重的问题,全世界每年影响3-5亿人,尤其是5岁以下的儿童。世界上70%的人口在其初级保健中使用传统和土著医学。这些土著补救措施的事实是口头通过的,有时是作为文件通过的。自古以来,阿育吠陀是东南亚国家/地区的主要康复系统。印度的阿育吠陀文献和其他书籍都声称几种植物在治疗腹泻方面的功效。随着全球范围内阿育吠陀医学的发展,对它们的作用的科学依据的兴趣也在不断增加。研究人员正在进行实验,以建立所声称的作用与观察到的药理活性之间的关系。在本文中,试图汇编用于治愈阿育吠陀腹泻的药用植物的科学基础。通过电子搜索(PubMed,ScienceDirect,Medline和Google Scholar)从发表的文章中收集了文献,这些文章报道了阿育吠陀经典中提到的植物的止泻活性。据报道,共有58个科的109种植物具有止泻作用。几种印度药用植物已显示出有希望的止泻作用,但是对这些植物的止泻潜力的研究并未超出概念验证阶段。由于该领域知识的匮乏,希望本文能够刺激未来的临床研究。

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