An active principle of Nigella sativa L. thymoquinone showing significant antimicrobial activity against anaerobic bacteria

机译：苜蓿百里醌的活性成分对厌氧菌显示出显着的抗菌活性

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Aim/Background:Thymoquinone (TQ) is the major active principle of Nigella sativa seed (black seed) and is known to control many fungi, bacteria, and some viruses. However, the activity of TQ against anaerobic bacteria is not well demonstrated. Anaerobic bacteria can cause severe infections, including diarrhea, aspiration pneumonia, and brain abscess, particularly in immunodeficient individuals. The present study aimed to investigate the in vitro antimicrobial activity of TQ against some anaerobic pathogens in comparison to metronidazole.

机译：目的/背景：胸腺醌（TQ）是黑变种种子（黑种子）的主要活性成分，已知能控制许多真菌，细菌和某些病毒。但是，TQ对厌氧细菌的活性尚未得到充分证明。厌氧细菌会引起严重的感染，包括腹泻，吸入性肺炎和脑脓肿，尤其是在免疫缺陷的个体中。本研究旨在研究与甲硝唑相比，TQ对某些厌氧性病原体的体外抗菌活性。

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期刊名称 Journal of Intercultural Ethnopharmacology
作者
Mohammad Akram Randhawa; Awwad Khalaf Alenazy; Majed Gorayan Alrowaili; Jamith Basha;
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作者单位

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年(卷),期 2017(6),1
年度 2017
页码 97–101
总页数 5
原文格式 PDF
正文语种
中图分类
关键词
Brucella blood agar metronidazole minimum inhibitory concentrations Nigella sativa thymoquinone;

机译：布鲁氏菌血琼脂;甲硝唑;最低抑菌浓度;苜蓿黑斑病;胸腺醌;

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1. An active principle of Nigella sativa L., thymoquinone, showing significant antimicrobial activity against anaerobic bacteria [J] . Mohammad Akram Randhawa, Awwad Khalaf Alenazy, Majed Gorayan Alrowaili, Journal of Intercultural Ethnopharmacology . 2017,第1期

机译：苜蓿百里醌的活性成分，对厌氧菌显示出显着的抗菌活性
2. Chemical composition, antimicrobial potential against cariogenic bacteria and cytotoxic activity of Tunisian Nigella sativa essential oil and thymoquinone [J] . Hanene Jrah Harzallah, Bochra Kouidhi, Guido Flamini, Food Chemistry . 2011,第4期

机译：突尼斯尼古拉苜蓿精油和胸腺醌的化学组成，对生龋菌的抗菌潜力和细胞毒活性
3. Leishmanicidal and cytotoxic activities of Nigella sativa and its active principle, thymoquinone [J] . Mahmoudvand Hossein, Tavakoli Razieh, Sharififar Fariba, Pharmaceutical Biology . 2015,第7a12期

机译：苜蓿和其有效成分胸腺醌的杀菌和细胞毒活性
4. Black Cumin (Nigella sativa L.) and Awar-Awar (Ficus septica Burm. F.) Combination Extract Inhibits Proliferation and Modulates Cell Cycle on HeLa Cell [C] . Ragil Anang Santoso, Amadea Sylva Lienaningrum, Eunice Dwininta Bangun, International Conference on Bioinformatics, Biotechnology, and Biomedical Engineering . 2019

机译：黑雀（Nigella Sativa L.）和Awar-Awar（Ficus Septica Burm.F.）组合提取物抑制了HeLa细胞上的增殖和调节细胞周期
5. Targeted killing of bacteria by conjugation of a soluble photosensitizer to an antimicrobial peptide: Principles and mechanisms. [D] . Johnson, Gregory Andrew. 2013

机译：通过将可溶性光敏剂与抗菌肽结合来有针对性地杀死细菌：原理和机理。
6. Antibacterial activity of Thymoquinone an active principle of Nigella sativa and its potency to prevent bacterial biofilm formation [O] . Kamel Chaieb, Bochra Kouidhi, Hanene Jrah, 2011

机译：苜蓿的活性成分胸腺醌的抗菌活性及其防止细菌生物膜形成的功效
7. Antibacterial activity of Thymoquinone, an active principle of Nigella sativa and its potency to prevent bacterial biofilm formation [O] . Bakhrouf Amina, Mahdouani Kacem, Jrah Hanene, 2011

机译：苜蓿的活性成分胸腺醌的抗菌活性及其防止细菌生物膜形成的功效

An active principle of Nigella sativa L. thymoquinone showing significant antimicrobial activity against anaerobic bacteria

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