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Commissioning and initial experience with the first clinical gantry‐mounted proton therapy system

机译:使用首个临床龙门式质子治疗系统的调试和初步经验

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摘要

The purpose of this study is to describe the comprehensive commissioning process and initial clinical experience of the Mevion S250 proton therapy system, a gantry‐mounted, single‐room proton therapy platform clinically implemented in the S. Lee Kling Proton Therapy Center at Barnes‐Jewish Hospital in St. Louis, MO, USA. The Mevion S250 system integrates a compact synchrocyclotron with a C‐inner gantry, an image guidance system and a 6D robotic couch into a beam delivery platform. We present our commissioning process and initial clinical experience, including i) CT calibration; ii) beam data acquisition and machine characteristics; iii) dosimetric commissioning of the treatment planning system; iv) validation through the Imaging and Radiation Oncology Core credentialing process, including irradiations on the spine, prostate, brain, and lung phantoms; v) evaluation of localization accuracy of the image guidance system; and vi) initial clinical experience. Clinically, the system operates well and has provided an excellent platform for the treatment of diseases with protons.PACS number(s): 87.55.ne, 87.56.bd
机译:这项研究的目的是描述Mevion S250质子治疗系统的全面调试过程和初步临床经验,Mevion S250质子治疗系统是在Barnes-Jewish的S. Lee Kling质子治疗中心临床实施的龙门式单室质子治疗平台美国密苏里州圣路易斯的医院。 Mevion S250系统将紧凑的同步回旋加速器与C型内机架,图像引导系统和6D机器人卧榻集成到光束传输平台中。我们介绍我们的调试过程和初步的临床经验,包括:i)CT校准; ii)光束数据采集和机器特性; iii)剂量委托调试治疗计划系统; iv)通过影像和放射肿瘤学核心资格认证过程进行验证,包括对脊柱,前列腺,大脑和肺部体模进行辐射; v)评估图像导航系统的定位精度; vi)最初的临床经验。临床上,该系统运行良好,并为质子疾病的治疗提供了一个出色的平台。PACS号:87.55.ne,87.56.bd

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