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Mouse Resource Browser—a database of mouse databases

机译:鼠标资源浏览器-鼠标数据库的数据库

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摘要

The laboratory mouse has become the organism of choice for discovering gene function and unravelling pathogenetic mechanisms of human diseases through the application of various functional genomic approaches. The resulting deluge of data has led to the deployment of numerous online resources and the concomitant need for formalized experimental descriptions, data standardization, database interoperability and integration, a need that has yet to be met. We present here the Mouse Resource Browser (MRB), a database of mouse databases that indexes 217 publicly available mouse resources under 22 categories and uses a standardised database description framework (the CASIMIR DDF) to provide information on their controlled vocabularies (ontologies and minimum information standards), and technical information on programmatic access and data availability. Focusing on interoperability and integration, MRB offers automatic generation of downloadable and re-distributable SOAP application-programming interfaces for resources that provide direct database access. MRB aims to provide useful information to both bench scientists, who can easily navigate and find all mouse related resources in one place, and bioinformaticians, who will be provided with interoperable resources containing data which can be mined and integrated.>Database URL:
机译:通过使用各种功能基因组方法,实验室小鼠已成为发现基因功能和揭示人类疾病致病机制的首选生物。随之而来的大量数据导致大量在线资源的部署以及随之而来的对形式化实验说明,数据标准化,数据库互操作性和集成的需求,这些需求尚未得到满足。我们在这里展示了鼠标资源浏览器(MRB),它是一个鼠标数据库数据库,为22个类别下的217个公共可用鼠标资源建立索引,并使用标准化的数据库描述框架(CASIMIR DDF)来提供有关其受控词汇表的信息(本体和最小信息)标准),以及有关程序访问和数据可用性的技术信息。专注于互操作性和集成,MRB为可直接访问数据库的资源自动生成可下载和可重新分配的SOAP应用程序编程接口。 MRB的目的是为既可以轻松地在一个地方导航和查找所有与鼠标相关的资源的台式科学家,又为将提供包含可挖掘和集成数据的可互操作资源的生物信息学家提供有用的信息。>数据库URL < / strong>:

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