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Characterization of SnO2-based 68Ge/68Ga generators and 68Ga-DOTATATE preparations: radionuclide purity radiochemical yield and long-term constancy

机译：基于SnO2的68Ge / 68Ga发生器和68Ga-DOTATATE制剂的表征：放射性核素纯度放射化学收率和长期恒定性

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摘要

BackgroundWith the increasing utilization of ⁶⁸Ge-⁶⁸Ga radionuclide generators, ⁶⁸Ga labelled peptides like DOTATATE are receiving more attention in nuclear medicine. On the one hand, the long half-life of the parent nuclide ⁶⁸Ge is an enormous advantage for routine applications, but the question of the long-term stability of the ⁶⁸Ge breakthrough arises, which up to now has scarcely been investigated.

机译：背景技术随着^{68 Ge- ^{68 Ga放射性核素产生剂利用的增加，^{68 Ga标记的肽如DOTATATE在核医学中受到越来越多的关注。一方面，亲核素^{68 Ge的长半衰期对于常规应用是一个巨大的优势，但是^{68 的长期稳定性问题锗的突破出现了，到目前为止还没有进行过研究。}}}}}

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期刊名称 EJNMMI Research
作者
Ferdinand Sudbrock; Thomas Fischer; Beate Zimmermanns; Mehrab Guliyev; Markus Dietlein; Alexander Drzezga; Klaus Schomäcker;
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作者单位

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年(卷),期 2014(4),-1
年度 2014
页码 36
总页数 10
原文格式 PDF
正文语种
中图分类
关键词
68Ge-68Ga radionuclide generator Radionuclide purity Gamma-ray spectrometry PET;

机译：68Ge-68Ga放射性核素发生器放射性核素纯度伽马射线光谱法PET;

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专利

1. Characterization of SnO ₂-based 68Ge/ 68Ga generators and 68Ga-DOTATATE preparations: radionuclide purity, radiochemical yield and long-term constancy [J] . Ferdinand Sudbrock, Thomas Fischer, Beate Zimmermanns, EJNMMI Research . 2014,第1期

机译：基于SnO _{2 的 68 Ge / 68 Ga发生器和 68 Ga-DOTATATE制剂的表征：放射性核素纯度，放射化学收率和长期恒定性}
2. Preparation and evaluation of SnO2-based 68Ge/68Ga generator made from 68Ge produced through natZn(α,xn) reaction [J] . SahaDasS., ChattopadhyayS., AlamM., Applied radiation and isotopes: including data, instrumentation and methods for use in agriculture, industry and medicine . 2013,第Null期

机译：由natZn（α，xn）反应生成的68Ge制成的SnO2基68Ge / 68Ga发生器的制备和评估
3. Scaled-up radiolabelling of DOTATATE with 68Ga eluted from a SnO2-based 68Ge/68Ga generator. [J] . Rossouw DD, Breeman WA Applied radiation and isotopes: including data, instrumentation and methods for use in agriculture, industry and medicine . 2012,第1期

机译：从基于SnO2的68Ge / 68Ga发生器洗脱的68Ga放大放大DOTATATE的放射性标记。
4. Preparation Of Radium And Other Spent Sealed Sources Containing Long-Lived Radionuclides To Long-Term Storage [C] . Waste management symposium . 2003

机译：纳米镭的制备和其他含有长的放射性核素的密封源以长期储存
5. Preparation & characterization of high purity Cu2 ZnSn(SxSe1-x)4 nanoparticles [D] . Negash, Bethlehem G. 2014

机译：高纯度Cu2 ZnSN（SXSE1-X）4纳米粒子的制备与表征
6. Radiosynthesis of clinical doses of 68Ga-DOTATATE (GalioMedix™) and validation of organic-matrix-based 68Ge/68Ga generators [O] . Izabela Tworowska, David Ranganathan, Sanjay Thamake, -1

机译：临床剂量68Ga-DOTATATE（GalioMedix™）的放射合成以及基于有机基质的68Ge / 68Ga发生器的验证
7. Characterization of SnO2-based 68Ge/68Ga generators and 68Ga-DOTATATE preparations: radionuclide purity, radiochemical yield and long-term constancy [O] . Ferdinand Sudbrock, Thomas Fischer, Beate Zimmermanns, 2014

机译：基于SnO2的68Ge / 68Ga发生器和68Ga-DOTATATE制剂的表征：放射性核素纯度，放射化学收率和长期恒定性
8. Preparation of Radium and Other Spent Sealed Sources Containing Long-Lived Radionuclides to Long-Term Storage [R] . Arustamov, A. E., Ojovan, M. I., Semenov, K. N., 2003

机译：含有长寿命放射性核素的镭和其他废旧密封源的制备

Characterization of SnO2-based 68Ge/68Ga generators and 68Ga-DOTATATE preparations: radionuclide purity radiochemical yield and long-term constancy

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