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Time series analysis as input for clinical predictive modeling: Modeling cardiac arrest in a pediatric ICU

机译:时间序列分析作为临床预测建模的输入:在儿科ICU中建模心脏骤停

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摘要

BackgroundThousands of children experience cardiac arrest events every year in pediatric intensive care units. Most of these children die. Cardiac arrest prediction tools are used as part of medical emergency team evaluations to identify patients in standard hospital beds that are at high risk for cardiac arrest. There are no models to predict cardiac arrest in pediatric intensive care units though, where the risk of an arrest is 10 times higher than for standard hospital beds. Current tools are based on a multivariable approach that does not characterize deterioration, which often precedes cardiac arrests. Characterizing deterioration requires a time series approach. The purpose of this study is to propose a method that will allow for time series data to be used in clinical prediction models. Successful implementation of these methods has the potential to bring arrest prediction to the pediatric intensive care environment, possibly allowing for interventions that can save lives and prevent disabilities.
机译:背景技术每年有成千上万的儿童在小儿重症监护室经历心脏骤停事件。这些孩子大多数死了。心脏骤停预测工具被用作医疗急救小组评估的一部分,以识别标准医院病床中发生心脏骤停高风险的患者。但是,没有模型可以预测小儿重症监护室的心脏骤停,其发生心脏骤停的风险是标准医院病床的10倍。当前的工具基于多变量方法,该方法不能表征恶化,而恶化通常发生在心脏骤停之前。表征劣化需要时间序列方法。这项研究的目的是提出一种方法,该方法将允许在临床预测模型中使用时间序列数据。这些方法的成功实施可能将逮捕预测带入儿科重症监护环境,可能允许采取能够挽救生命并预防残疾的干预措施。

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