首页> 美国卫生研究院文献>Advances in Radiation Oncology >First-In-Human Phase 1 Study of a Nonwoven Fabric Bioabsorbable Spacer for Particle Therapy: Space-Making Particle Therapy (SMPT)

【2h】

First-In-Human Phase 1 Study of a Nonwoven Fabric Bioabsorbable Spacer for Particle Therapy: Space-Making Particle Therapy (SMPT)

机译：非织造布生物可吸收垫片用于颗粒疗法的人类首次阶段1研究：造空颗粒疗法（SMPT）

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

PurposeSurgical spacer placement (SSP) is useful in particle therapy (PT) for patients with abdominal or pelvic tumors located adjacent to normal organs. We developed a nonwoven fabric bioabsorbable spacer made of polyglycolic acid (PGA) sutures that degrades via hydrolysis. We then conducted this first-in-human phase 1 study of the combination of SSP and PT using the PGA spacer, which we termed space-making PT (SMPT). This study aimed to evaluate the safety and efficacy of SMPT in patients with unresectable malignant tumor located adjacent to normal organs.

机译：目的外科间隔垫片放置（SSP）在颗粒疗法（PT）中可用于腹部或骨盆肿瘤位于正常器官附近的患者。我们开发了一种由聚乙醇酸（PGA）缝线制成的可生物吸收的非织造垫片，该垫片可通过水解而降解。然后，我们使用PGA隔片对SSP和PT进行了人类的第一阶段研究，我们将其称为航天PT（SMPT）。这项研究旨在评估SMPT在无法切除的恶性肿瘤中邻近正常器官的患者中的安全性和有效性。

著录项

期刊名称 Advances in Radiation Oncology
作者
Ryohei Sasaki; Yusuke Demizu; Tomohiro Yamashita; Shohei Komatsu; Hiroaki Akasaka; Daisuke Miyawaki; Kenji Yoshida; Tianyuan Wang; Tomoaki Okimoto; Takumi Fukumoto;
展开▼
作者单位

展开▼
年(卷),期 2019(4),4
年度 2019
页码 729–737
总页数 9
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词

相似文献

外文文献
中文文献
专利

1. First-In-Human Phase 1 Study of a Nonwoven Fabric Bioabsorbable Spacer for Particle Therapy: Space-Making Particle Therapy (SMPT) [J] . Ryohei Sasaki, Yusuke Demizu, Tomohiro Yamashita, Advances in Radiation Oncology . 2019,第4期

机译：非织造布生物可吸收垫片在人类中的第1阶段研究：粒子制造太空疗法（SMPT）
2. First-in-Human Phase I Study of a Non-Woven Fabric Bioabsorbable Spacer Combined with Particle Therapy Against Abdominal or Pelvic Sarcomas [J] . Sasaki R., Demizu Y., Yamashita T., International Journal of Radiation Oncology, Biology, Physics . 2019,第1Suppla期

机译：第一阶段I研究非织造织物生物可吸收间隔物与腹部或盆腔肉瘤联合颗粒治疗
3. Space-Making Particle Therapy with Surgical Spacer Placement in Patients with Sacral Chordoma [J] . Tsugawa Daisuke, Komatsu Shohei, Demizu Yusuke, Journal of the American College of Surgeons . 2020,第2期

机译：骶骨脊髓瘤患者手术间隔术治疗空间颗粒疗法
4. In vitro study of PLGA/PFH particles loaded with gold nanoparticles as theranostic agents for photoacoustic imaging and cancer therapy [C] . Wang Yan J., Strohm Eric M., Kolios Michael C., IEEE International Ultrasonics Symposium . 2014

机译：载有金纳米颗粒作为治疗试剂的PLGA / PFH颗粒的体外研究，用于光声成像和癌症治疗
5. Smart Brachytherapy Spacers for Combined Chemo-Radiation Therapy: Local Delivery of Nanoparticles, Chemotherapeutics, and Molecular Inhibitors for Cancer Treatment [D] . Belz, Jodi Elizabeth. 2017

机译：用于组合化疗疗法的智能近距离放射治疗：纳米粒子，化学治疗剂和分子抑制剂的局部递送癌症治疗
6. Use of the NASA Space Radiation Laboratory at Brookhaven National Laboratory to Conduct Charged Particle Radiobiology Studies Relevant to Ion Therapy [O] . Kathryn D. Held, Eleanor A. Blakely, Michael D. Story, -1

机译：使用布鲁克黑文国家实验室的NASA空间辐射实验室进行与离子治疗有关的带电粒子放射生物学研究
7. First-in-Human Phase I Study of a Non-Woven Fabric Bioabsorbable Spacer Combined with Particle Therapy Against Abdominal or Pelvic Sarcomas [O] . R. Sasaki, Y. Demizu, T. Yamashita, 2019

机译：第一阶段I研究非织造织物生物可吸收间隔物与腹部或盆腔肉瘤联合颗粒治疗

First-In-Human Phase 1 Study of a Nonwoven Fabric Bioabsorbable Spacer for Particle Therapy: Space-Making Particle Therapy (SMPT)

摘要

著录项

相似文献

相关主题

期刊订阅