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Complexities in the Atrial Fibrillation-Stroke Relationship: Improving Comprehension of Temporal Discordance Magnitude Synergism and Subclinical Atrial Fibrillation -- Three Sources of Consternation for Physicians Who Care for Patients with Atrial Fibrillation

机译：心房颤动-卒中关系的复杂性：提高对时间不一致幅度协同作用和亚临床心房颤动的理解-护理心房颤动患者的医师的三种养生来源

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That clinically-documented atrial fibrillation (AF) in association with a variety of elevated clinical/laboratory risk markers is associated with an increased risk of stroke is well known -- regardless of whether the AF is paroxysmal, persistent, or permanent. Moreover, data is accumulating to suggest that the absolute rate of stroke should be expectedly higher with a greater burden of AF and greater degree of comorbid contributors. Relatedly, stroke prevention with chronic oral anticoagulation (OAC) is recommended for AF patients with appropriate risk markers by all major medical, cardiologic, and surgical guideline-writing organizations. However, at least two major clinical concerns about the above AF-stroke statements remain. First, if AF is related to stroke, why then is there not a consistent temporal relationship between a stroke and AF? Second, is there importance to and what should we do about device-detected AF (so-called subclinical AF [SCAF]) in the absence of clinically-recognized AF? This paper is designed to enhance the understanding of these issues and reduce the consternation of physicians who care for patients with AF with respect to them.

机译：众所周知，无论房颤是阵发性，持续性还是永久性的，临床记录的房颤（AF）与各种升高的临床/实验室风险标志物都与中风风险增加相关。此外，越来越多的数据表明，卒中的绝对发生率应更高，房颤负担更大，合并症的发生率也更高。相关地，所有主要的医学，心脏病学和外科手术指南编写组织都建议对具有适当危险标志物的房颤患者推荐使用慢性口服抗凝（OAC）预防中风。然而，关于上述AF中风的陈述至少有两个主要的临床问题。首先，如果AF与中风有关，那么为什么中风和AF之间没有一致的时间关系？第二，在没有临床公认的AF的情况下，对于设备检测到的AF（所谓的亚临床AF [SCAF]）是否重要，我们该怎么办？本文旨在增强对这些问题的理解，并减少照顾AF患者的医师的疑虑。

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作者
James A. Reiffel;
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年(卷),期 -1(11),2
年度 -1
页码 2100
总页数 3
原文格式 PDF
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Atrial Fibrillation Magnitude Synergism Temporal Discordance Subclinical Atrial Fibrillation;

机译：心房颤动;幅度协同作用;时间不一致;亚临床心房颤动;

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1. Complexities in the Atrial Fibrillation-Stroke Relationship: Improving Comprehension of Temporal Discordance, Magnitude Synergism, and Subclinical Atrial Fibrillation -- Three Sources of Consternation for Physicians Who Care for Patients with Atrial Fibrillation [J] . James A. Reiffel Journal of Atrial Fibrillation . 2018,第2期

机译：心房颤动-卒中关系的复杂性：提高对时间不一致，幅度协同作用和亚临床心房颤动的理解-护理心房颤动患者的医师的三种养生来源
2. Stroke type and severity in patients with subclinical atrial fibrillation: An analysis from the Asymptomatic Atrial Fibrillation and Stroke Evaluation in Pacemaker Patients and the Atrial Fibrillation Reduction Atrial Pacing Trial (ASSERT) [J] . Kanjana S. Perera, Mukul Sharma, Stuart J. Connolly, The American heart journal . 2018,第期

机译：亚临床心房颤动患者中风型和严重程度：起搏器患者无症状心房颤动和中风评价的分析及心房颤动降低心房起搏试验（断言）
3. Use of Evidence-Based Therapy for Cardiovascular Risk Factors in Canadian Outpatients With Atrial Fibrillation From the Facilitating Review and Education to Optimize Stroke Prevention in Atrial Fibrillation (FREEDOM AF) and Co-ordinated National Network to Engage Physicians in the Care and Treatment of Patients With Atrial Fibrillation (CONNECT AF) [J] . Silberberg Alexandra, Tan Mary K., Yan Andrew T., The American Journal of Cardiology . 2017,第4期

机译：从促进审查和教育中的心房颤动，在促进审查和教育中使用基于循证血管危险因素的使用，从而优化心房颤动（FREDOM AF）和协调国家网络的卒中预防，从事医生在护理和治疗患者中心房颤动（连接AF）
4. Impact of three dimensional atrial fibrosis on development and stability of rotational and focal sources in atrial fibrillation — A 3D simulation and clinical high-density mapping study in persistent atrial fibrillation [C] . Markus Rottmann, Viktor Markstein, Ufuk Arslan, Computing in Cardiology Conference . 2016

机译：三维房颤对房颤中旋转和局灶性源的发展和稳定性的影响—持续性房颤的3D模拟和临床高密度标测研究
5. Optimal Post-Procedural Therapy for Patients Ineligble for Treatment with Oral Anticoagulatiion Who Undergo Left Atrial Appendage Occlusion with the Watchman Device for Non-Valvular Atrial Fibrillation [D] . Whitehead, Kristen Marie. 2020

机译：用口腔抗凝血治疗患者患者的最佳过程治疗患者患有左心房阑尾闭塞与鹰刀用于非瓣膜心房颤动
6. Compliance of Atrial Fibrillation Treatment with the Atrial Fibrillation Better Care (ABC) Pathway Improves the Clinical Outcomes in the Middle East Population: A Report from the Gulf Survey of Atrial Fibrillation Events (SAFE) Registry [O] . Jakub Gumprecht, Magdalena Domek, Marco Proietti, 2020

机译：房颤更好护理（ABC）途径对房颤治疗的依从性改善了中东人群的临床结果：海湾房颤事件（SAFE）海湾调查报告
7. ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation31This document was approved by the American College of Cardiology Board of Trustees in August 2001, the American Heart Association Science Advisory and Coordinating Committee in August 2001, and the European Society of Cardiology Board and Committee for Practice Guidelines and Policy Conferences in August 2001.32When citing this document, the American College of Cardiology, the American Heart Association, and the European Society of Cardiology would appreciate the following citation format: Fuster V, Rydén LE, Asinger RW, Cannom DS, Crijns HJ, Frye RL, Halperin JL, Kay GN, Klein WW, Lévy S, McNamara RL, Prystowsky EN, Wann LS, Wyse DG. ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines and Policy Conferences (Committee to Develop Guidelines for the Management of Patients With Atrial Fibrillation). J Am Coll Cardiol 2001;38:XX-XX.33This document is available on the World Wide Web sites of the American College of Cardiology (www.acc.org), the American Heart Association (www.americanheart.org), the European Society of Cardiology (www.escardio.org), and the North American Society of Pacing and Electrophysiology (www.naspe.org). Single reprints of this document (the complete Guidelines) to be published in the mid-October issue of the European Heart Journal are available by calling +44.207.424.4200 or +44.207.424.4389, faxing +44.207.424.4433, or writing Harcourt Publishers Ltd, European Heart Journal, ESC Guidelines – Reprints, 32 Jamestown Road, London, NW1 7BY, United Kingdom. Single reprints of the shorter version (Executive Summary and Summary of Recommendations) published in the October issue of the Journal of the American College of Cardiology and the October issue of Circulation, are available for $5.00 each by calling 800-253-4636 (US only) or by writing the Resource Center, American College of Cardiology, 9111 Old Georgetown Road, Bethesda, Maryland 20814. To purchase bulk reprints specify version and reprint number (Executive Summary 71-0208; full text 71-0209) up to 999 copies, call 800-611-6083 (US only) or fax 413-665-2671; 1000 or more copies, call 214-706-1466, fax 214-691-6342; or E-mail: pubauth@heart.org. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines and Policy Conferences (Committee to Develop Guidelines for the Management of Patients With Atrial Fibrillation) Developed in Collaboration With the North American Society of Pacing and Electrophysiology [O] . Fuster Valentin, Rydén Lars E., Asinger Richard W., 2001

机译：ACC / AHA / ESC治疗房颤患者指南31该文件于2001年8月获得美国心脏病学会董事会，2001年8月美国心脏协会科学咨询与协调委员会以及欧洲心脏病学会的批准以及实践指南和政策委员会会议（2001年8月）。32引用本文件时，美国心脏病学会，美国心脏协会和欧洲心脏病学会将赞赏以下引用格式：Fuster V，RydénLE，Asinger RW，Cannom DS，Crijns HJ，Frye RL，Halperin JL，Kay GN，Klein WW，LévyS，McNamara RL，Prystowsky EN，Wann LS，Wyse DG。 ACC / AHA / ESC治疗房颤患者的指南：美国心脏病学会/美国心脏协会实践指南工作组和欧洲心脏病学会实践指南委员会和政策会议的报告（制定指南委员会）用于房颤患者的治疗）。 J Am Coll Cardiol 2001; 38：XX-XX.33本文件可在美国心脏病学会（www.acc.org），美国心脏协会（www.americanheart.org），欧洲的万维网站点上找到心脏病学会（www.escardio.org）和北美起搏和电生理学会（www.naspe.org）。可致电+44.207.424.4200或+44.207.424.4389，传真+44.207.424.4433或写信给Harcourt Publishers，以获取本文档（完整的准则）的单份重印本（完整的准则），该印刷本将于10月中旬出版。欧洲心脏杂志，ESC指南–转载，英国伦敦詹姆斯敦路32号，NW1 7BY。短版（执行摘要和建议摘要）的单版重印在《美国心脏病学会杂志》十月刊和《循环》十月刊上，致电800-253-4636（仅美国），每本售价5.00美元。）或写信给美国心脏病学院资源中心，地址是：马里兰州贝塞斯达市Old Georgetown Road 9111，邮编20814。要购买批量转载，请指定版本和转载编号（执行摘要71-0208；全文71-0209），最多999份，致电800-611-6083（仅限美国）或传真413-665-2671； 1000或更多副本，请致电214-706-1466，传真214-691-6342;或电子邮件：pubauth@heart.org。美国心脏病学会/美国心脏协会实践指南工作组和欧洲心脏病学会实践指南和政策会议（制定房颤患者治疗指南委员会）的报告是与北方合作开发的美国起搏与电生理学会

Complexities in the Atrial Fibrillation-Stroke Relationship: Improving Comprehension of Temporal Discordance Magnitude Synergism and Subclinical Atrial Fibrillation -- Three Sources of Consternation for Physicians Who Care for Patients with Atrial Fibrillation

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