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Reliability and validity of the World Health Organization reading standards for paediatric chest radiographs used in the field in an impact study of Pneumococcal Conjugate Vaccine in Kilifi Kenya

机译:世界卫生组织在肯尼亚基利菲开展的肺炎球菌共轭疫苗影响研究中使用的小儿胸部X光片阅读标准的信度和效度

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摘要

BackgroundRadiologically-confirmed pneumonia (RCP) is a specific end-point used in trials of Pneumococcal Conjugate Vaccine (PCV) to estimate vaccine efficacy. However, chest radiograph (CXR) interpretation varies within and between readers. We measured the repeatability and reliability of paediatric CXR interpretation using percent agreement and Cohen’s Kappa and the validity of field readings against expert review in a study of the impact of PCV on pneumonia.
机译:背景放射确诊的肺炎(RCP)是肺炎球菌结合疫苗(PCV)试验中用于评估疫苗功效的特定终点。但是,胸部X线片(CXR)的解释在读者内部和读者之间有所不同。在PCV对肺炎的影响研究中,我们使用百分比一致性和Cohen's Kappa测量了儿科CXR解释的可重复性和可靠性,以及针对专家评审的野外读数有效性。

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