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Hyperprolactinemia with Galactorrhea Due to Subclinical Hypothyroidism: A Case Report and Review of Literature

机译：亚临床甲状腺功能减退导致的高泌乳素血症合并溢乳：一例病例报告并文献复习

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摘要

Hyperprolactinemia is a common finding in primary hypothyroidism, but increased prolactin in the setting of subclinical hypothyroidism (SCH) has been scarcely reported in the literature. This is a rare case of hyperprolactinemia due to SCH that resolved with thyroid hormone replacement therapy. The patient was not on any medications known to cause hyperprolactinemia but she was using isoniazid for her latent tuberculosis. Isoniazid therapy may explain breast pain, but there is no reported relationship between isoniazid use causing subclinical hypothyroidism and hyperprolactinemia. A literature review reveals that few cases of galactorrhea associated with subclinical hypothyroidism have been reported. Similar to the reported cases in the literature, our patient’s thyroid stimulating hormone (TSH) and prolactin levels returned to normal with levothyroxine therapy.
机译：高泌乳素血症是原发性甲状腺功能减退症的常见发现，但是在亚临床甲状腺功能减退症（SCH）的情况下，催乳素水平升高的报道很少。这是罕见的高泌乳素血症病例，原因是SCH通过甲状腺激素替代疗法得以解决。该患者未使用任何已知会引起高泌乳素血症的药物，但她正在使用异烟肼治疗潜伏性结核。异烟肼疗法可能解释了乳房疼痛，但尚无使用异烟肼引起亚临床甲状腺功能减退症和高泌乳素血症的相关报道。文献综述显示，很少有病例报道与亚临床甲状腺功能减退有关的溢乳。与文献报道的病例相似，左甲状腺素治疗可使我们患者的甲状腺刺激激素（TSH）和催乳素水平恢复正常。

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