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Evidence-Based Cutoff Threshold Values from Receiver Operating Characteristic Curve Analysis for Knee Osteoarthritis in the 50-Year-Old Korean Population: Analysis of Big Data from the National Health Insurance Sharing Service

机译:50岁韩国人群膝骨关节炎接受者操作特征曲线分析的基于证据的阈值阈值:国家健康保险共享服务的大数据分析

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摘要

We aimed to investigate the characteristics of patients with osteoarthritis (OA), using the data of all Koreans registered in the National Health Insurance Sharing Service Database (NHISS DB), and to provide ideal alternative cutoff thresholds for alleviating OA symptoms. Patients with OA (codes M17 and M17.1–M17.9 in the Korean Standard Classification of Disease and Causes of Death) were analyzed using SAS software. Optimal cutoff thresholds were determined using receiver operating characteristic curve analysis. The 50-year age group was the most OA pathogenic group (among 40~70 years, n = 2088). All exercise types affected the change of body mass index (p < 0.05) and the sex difference in blood pressure (BP) (p < 0.01). All types of exercise positively affected the loss of waist circumference and the balance test (standing time on one leg in seconds) (p < 0.01). The cutoff threshold for the time in seconds from standing up from a chair to walking 3 m and returning to the same chair was 8.25 (80% sensitivity and 100% specificity). By using the exercise modalities, categorized multiple variables, and the cutoff threshold, an optimal alternative exercise program can be designed for alleviating OA symptoms in the 50-year age group.
机译:我们旨在使用在国家健康保险共享服务数据库(NHISS DB)中注册的所有韩国人的数据来调查骨关节炎(OA)患者的特征,并为缓解OA症状提供理想的替代阈值。使用SAS软件分析了OA患者(韩国疾病和死亡原因标准分类中的代码M17和M17.1–M17.9)。使用接收器工作特性曲线分析确定最佳截止阈值。 50岁年龄组是最常见的OA致病组(40〜70岁,n = 2088)。所有运动类型均会影响体重指数(p <0.05)和血压性别差异(BP)的变化(p <0.01)。所有类型的运动都会对腰围的丧失和平衡测试(一只脚的站立时间以秒为单位)产生积极影响(p <0.01)。从椅子站起来到行走3毫米,再回到同一把椅子的时间阈值(以秒为单位)为8.25(灵敏度为80%,特异性为100%)。通过使用运动方式,分类的多个变量和临界值阈值,可以设计最佳的替代运动计划,以减轻50岁年龄组的OA症状。

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