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Reduced EEG Responses to Standard and Target Auditory Stimuli in Bipolar Disorder and the Impact of Psychotic Features: Analysis of ERPs Spectral Power and Inter-Trial Coherence

机译:减少对双相情感障碍的标准和目标听觉刺激的脑电图反应以及精神病特征的影响:ERP频谱功率和试验间一致性的分析

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摘要

BackgroundBipolar disorder (BD) is associated with reductions in the P3b event-related potential (ERP) to target auditory stimuli, which suggests deficits in context updating. Previous studies have typically examined these responses in the temporal domain, which may not capture alterations in specific frequencies of phase-locked or induced electrophysiological activity. Therefore, the present study examined early and late ERPs in temporal and frequency domains in a bipolar sample with and without current psychotic features.
机译:背景双相情感障碍(BD)与针对听觉刺激的P3b事件相关电位(ERP)降低相关,这表明背景更新存在缺陷。以前的研究通常在时域中检查这些响应,这些响应可能无法捕获锁相或诱发的电生理活动的特定频率的变化。因此,本研究在具有和不具有当前精神病特征的双相样本中在时域和频域检查了早期和晚期ERP。

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