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首页> 美国卫生研究院文献>other >Hematopoietic Stem Cell Transplantation Activity Worldwide in 2012 and a SWOT Analysis of the Worldwide Network for Blood and Marrow Transplantation Group (WBMT) including the global survey
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Hematopoietic Stem Cell Transplantation Activity Worldwide in 2012 and a SWOT Analysis of the Worldwide Network for Blood and Marrow Transplantation Group (WBMT) including the global survey

机译：2012年全球造血干细胞移植活动以及对全球血液和骨髓移植小组（WBMT）的SWOT分析包括全球调查

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Data on 68,146 hematopoietic stem cell transplants (HSCT) (53% autologous and 47% allogeneic) gathered by 1566 teams from 77 countries and reported through their regional transplant organizations were analyzed by main indication, donor type and stem cell source for the year 2012. With transplant rates ranging from 0.1 to 1001 per 10 million inhabitants, more HSCT were registered from unrelated 16,433 than related 15,493 donors. Grafts were collected from peripheral blood (66%), bone marrow (24%; mainly non-malignant disorders) and cord blood (10%). Compared to 2006, an increase of 46% total (57% allogeneic and 38% autologous) was observed. Growth was due to an increase in reporting teams (18%) and median transplant activity/team (from 38 to 48 HSCT/team). An increase of 67% was noted in mismatched/haploidentical family HSCT.A SWOT analysis revealed the global perspective of WBMT to be its major strength and identified potential to be the key professional body for patients and authorities. The limited data collection remains its major weakness and threat.In conclusion, global HSCT grows over the years without plateauing (allogeneic>autologous) and at different rates in the four WHO regions. Major increases were observed in allogeneic, haploidentical HSCT and, to a lesser extent, in cord blood.
机译：收集了来自77个国家的1566个小组的68146例造血干细胞移植（HSCT）的数据（自体的53％和同种异体的47％），并通过其区域移植组织报告了2012年的主要适应症，供体类型和干细胞来源。每1000万居民的移植率在0.1到1001之间，与无关的16,493个捐赠者相比，来自无关的16,433的HSCT登记数量更多。从外周血（66％），骨髓（24％；主要是非恶性疾病）和脐带血（10％）中收集移植物。与2006年相比，总计增加了46％（同种异体为57％，自体异体为38％）。增长归因于报告团队（18％）和中位数移植活动/团队（从38个HSCT /团队）增加。错配/单亲家庭HSCT增长了67％.SWOT分析显示，WBMT的全球优势是其主要优势，并已确定其潜力是患者和主管部门的关键专业机构。有限的数据收集仍然是其主要的弱点和威胁。总之，多年来，全球HSCT在四个世卫组织区域中没有平稳（同情>自体）增长且增长率不同。在同种异体，单倍体HSCT中观察到大量增加，而在脐血中观察到较小程度的增加。

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