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Patterns of database citation in articles and patents indicate long-term scientific and industry value of biological data resources

机译:文章和专利中数据库引用的模式表明了生物数据资源的长期科学和工业价值

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摘要

Data from open access biomolecular data resources, such as the European Nucleotide Archive and the Protein Data Bank are extensively reused within life science research for comparative studies, method development and to derive new scientific insights. Indicators that estimate the extent and utility of such secondary use of research data need to reflect this complex and highly variable data usage. By linking open access scientific literature, via Europe PubMedCentral, to the metadata in biological data resources we separate data citations associated with a deposition statement from citations that capture the subsequent, long-term, reuse of data in academia and industry.  We extend this analysis to begin to investigate citations of biomolecular resources in patent documents. We find citations in more than 8,000 patents from 2014, demonstrating substantial use and an important role for data resources in defining biological concepts in granted patents to both academic and industrial innovators. Combined together our results indicate that the citation patterns in biomedical literature and patents vary, not only due to citation practice but also according to the data resource cited. The results guard against the use of simple metrics such as citation counts and show that indicators of data use must not only take into account citations within the biomedical literature but also include reuse of data in industry and other parts of society by including patents and other scientific and technical documents such as guidelines, reports and grant applications.
机译:来自开放式生物分子数据资源的数据,例如欧洲核苷酸档案库和蛋白质数据库,已在生命科学研究中广泛用于比较研究,方法开发并获得新的科学见解。评估研究数据二次使用的程度和效用的指标需要反映这种复杂且高度可变的数据使用。通过将公开访问的科学文献(通过欧洲PubMedCentral)链接到生物数据资源中的元数据,我们将与沉积声明相关的数据引文与捕获学术界和工业界随后的长期数据复用的引文分开。我们将这一分析扩展到开始研究专利文献中生物分子资源的引用。自2014年以来,我们发现8,000多项专利被引用,这证明了数据资源在定义学术和工业创新者授予的专利中的生物学概念方面的大量使用和重要作用。结合我们的研究结果表明,生物医学文献和专利中的引用方式各不相同,这不仅是由于引用实践造成的,而且还取决于引用的数据资源。结果避免了使用简单的指标(例如引文计数),并且表明数据使用的指标不仅必须考虑生物医学文献中的引文,而且还必须通过包括专利和其他科学技术在内的行业和社会其他领域来重复使用数据。以及技术文件,例如指南,报告和拨款申请。

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