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Lessons learned: Infrastructure development and financial management for large publically funded international trials

机译:获得的经验:用于大型国际资助的国际试验的基础设施开发和财务管理

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摘要

Background/AimsRandomized clinical trials are widely recognized as essential to address world-wide clinical and public health research questions. However, for many conditions, their size and duration can overwhelm available public and private resources. To remain competitive in international research settings, advocates and practitioners of clinical trials must implement practices that reduce their cost. We identify approaches and practices for large, publicly-funded, international trials that reduce cost without compromising data integrity, and recommend an approach to cost reporting that permits comparison of clinical trials.
机译:背景/目的随机化临床试验是解决全球临床和公共卫生研究问题必不可少的工具。但是,在许多情况下,它们的大小和持续时间会淹没可用的公共和私人资源。为了在国际研究环境中保持竞争力,临床试验的倡导者和实践者必须采取降低成本的措施。我们确定大型的国际资助的国际试验的方法和实践,这些方法和实践可在不损害数据完整性的情况下降低成本,并建议一种允许比较临床试验的成本报告方法。

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