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首页> 美国卫生研究院文献>other >Computer-Aided Decision Support for Melanoma Detection Applied on Melanocytic and Nonmelanocytic Skin Lesions: A Comparison of Two Systems Based on Automatic Analysis of Dermoscopic Images
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Computer-Aided Decision Support for Melanoma Detection Applied on Melanocytic and Nonmelanocytic Skin Lesions: A Comparison of Two Systems Based on Automatic Analysis of Dermoscopic Images

机译：用于黑素细胞和非黑素细胞皮肤病变的黑色素瘤检测的计算机辅助决策支持：基于皮肤镜图像自动分析的两种系统的比较

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摘要

Commercially available clinical decision support systems (CDSSs) for skin cancer have been designed for the detection of melanoma only. Correct use of the systems requires expert knowledge, hampering their utility for nonexperts. Furthermore, there are no systems to detect other common skin cancer types, that is, nonmelanoma skin cancer (NMSC). As early diagnosis of skin cancer is essential, there is a need for a CDSS that is applicable to all types of skin lesions and is suitable for nonexperts. Nevus Doctor (ND) is a CDSS being developed by the authors. We here investigate ND's ability to detect both melanoma and NMSC and the opportunities for improvement. An independent test set of dermoscopic images of 870 skin lesions, including 44 melanomas and 101 NMSCs, were analysed by ND. Its sensitivity to melanoma and NMSC was compared to that of Mole Expert (ME), a commercially available CDSS, using the same set of lesions. ND and ME had similar sensitivity to melanoma. For ND at 95% melanoma sensitivity, the NMSC sensitivity was 100%, and the specificity was 12%. The melanomas misclassified by ND at 95% sensitivity were correctly classified by ME, and vice versa. ND is able to detect NMSC without sacrificing melanoma sensitivity.
机译：设计用于皮肤癌的可商购的临床决策支持系统（CDSS）仅用于检测黑色素瘤。正确使用系统需要专家知识，从而限制了它们对非专家的效用。此外，没有系统可以检测其他常见的皮肤癌类型，即非黑素瘤皮肤癌（NMSC）。由于皮肤癌的早期诊断是必不可少的，因此需要一种CDSS，该CDSS适用于所有类型的皮肤病变并且适合于非专家。 Nevus Doctor（ND）是由作者开发的CDSS。我们在这里调查ND检测黑素瘤和NMSC的能力以及改善的机会。 ND对包括44个黑色素瘤和101个NMSC在内的870个皮肤病变的皮肤镜图像的独立测试集进行了分析。使用相同的病变组，将其对黑素瘤和NMSC的敏感性与市售CDSS Mole Expert（ME）的敏感性进行了比较。 ND和ME对黑素瘤的敏感性相似。对于95％黑色素瘤敏感性的ND，NMSC敏感性为100％，特异性为12％。被ND在95％敏感性下误分类的黑素瘤由ME正确分类，反之亦然。 ND能够在不牺牲黑色素瘤敏感性的情况下检测NMSC。

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