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Putting the brakes on the drive to eat: Pilot effects of naltrexone and reward based eating on food cravings among obese women

机译:阻止进食:纳曲酮和奖励的先导作用是基于肥胖女性对食物的渴望而进食

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摘要

PurposeObese individuals vary in their experience of food cravings and tendency to engage in reward-driven eating, both of which can be modulated by the neural reward system rather than physiological hunger. We examined two predictions in a sample of obese women: (1) whether opioidergic blockade reduced food-craving intensity, and (2) whether opioidergic blockade reduced an association between food-craving intensity and reward-driven eating, which is a trait-like index of three factors (lack of control over eating, lack of satiation, preoccupation with food).
机译:目的肥胖者对食物的渴望和参与奖励驱动饮食的趋势各不相同,这两者都可以通过神经奖励系统而不是生理饥饿来调节。我们检查了肥胖女性样本中的两个预测:(1)阿片类药物能减少对食物的渴望,以及(2)阿片类药物能减少对食物的渴望和奖励饮食之间的联系,这是一种特质三个因素的指数(缺乏饮食控制,缺乏饱足感,对食物的关注)。

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