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Chronic Stress Induces a Hyporeactivity of the Autonomic Nervous System in Response to Acute Mental Stressor and Impairs Cognitive Performance in Business Executives

机译:慢性应激会诱发自主神经系统的高反应性以应对急性心理应激并削弱企业高管的认知能力

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摘要

The present study examined the incidence of chronic stress in business executives (109 subjects: 75 male and 34 female) and its relationship with cortisol levels, cognitive performance, and autonomic nervous system (ANS) reactivity after an acute mental stressor. Blood samples were collected from the subjects to measure cortisol concentration. After the sample collection, the subjects completed the Lipp Inventory of Stress Symptoms for Adults and the Stroop Color-Word Test to evaluate stress and cognitive performance levels, respectively. Saliva samples were collected prior to, immediately after, and five minutes after the test. The results revealed that 90.1% of the stressed subjects experienced stress phases that are considered chronic stress. At rest, the subjects with chronic stress showed higher cortisol levels, and no gender differences were observed. No differences were found between the stressed and non-stressed subjects regarding salivary amylase activity prior to test. Chronic stress also impaired performance on the Stroop test, which revealed higher rates of error and longer reaction times in the incongruent stimulus task independently of gender. For the congruent stimulus task of the Stroop test, the stressed males presented a higher rate of errors than the non-stressed males and a longer reaction time than the stressed females. After the acute mental stressor, the non-stressed male group showed an increase in salivary alpha-amylase activity, which returned to the initial values five minutes after the test; this ANS reactivity was not observed in the chronically stressed male subjects. The ANS responses of the non-stressed vs stressed female groups were not different prior to or after the Stroop test. This study is the first to demonstrate a blunted reactivity of the ANS when male subjects with chronic psychological stress were subjected to an acute mental stressor, and this change could contribute to impairments in cognitive performance.
机译:本研究调查了企业高管(109名受试者:75名男性和34名女性)中慢性应激的发生率,以及其与急性精神应激源后皮质醇水平,认知表现和自主神经系统(ANS)反应性的关系。从受试者收集血液样品以测量皮质醇浓度。收集样本后,受试者分别完成了成年人的Lipp压力症状量表和Stroop色词测试,以分别评估压力和认知能力水平。在测试之前,之后和之后五分钟收集唾液样品。结果显示,90.1%的压力对象经历了被认为是慢性压力的压力阶段。在休息时,患有慢性应激的受试者表现出较高的皮质醇水平,并且未观察到性别差异。在测试前,压力和非压力受试者唾液淀粉酶活性之间没有差异。长期压力也削弱了Stroop测试的性能,该测试显示,在与性别无关的不一致刺激任务中,错误率更高,反应时间更长。对于Stroop测试的一致刺激任务,压力大的男性比未压力大的男性呈现更高的错误率,并且反应时间比压力大的女性更长。急性精神压力后,无压力的男性组唾液α-淀粉酶活性增加,测试后五分钟恢复到初始值。在长期紧张的男性受试者中未观察到这种ANS反应性。在Stroop测试之前或之后,无压力与压力女性组的ANS反应无差异。这项研究首次证明,当患有慢性心理压力的男性受试者遭受急性心理压力时,ANS的反应性减弱,这种变化可能导致认知能力受损。

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