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Mercaptopropionic acid-capped Mn2+:ZnSe/ZnO quantum dots with both downconversion and upconversion emissions for bioimaging applications

机译:巯基丙酸封端的Mn2 +:ZnSe / ZnO量子点同时具有下转换和上转换发射适用于生物成像应用

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摘要

Doped quantum dots (d-dots) can serve as fluorescent biosensors and biolabels for biological applications. Our study describes a synthesis of mercaptopropionic acid (MPA)-capped Mn2+:ZnSe/ZnO d-dots through a facile, cost-efficient hydrothermal route. The as-prepared water-soluble d-dots exhibit strong emission at ca. 580 nm, with a photoluminescence quantum yield (PLQY) as high as 31%, which is the highest value reported to date for such particles prepared via an aqueous route. They also exhibit upconversion emission when excited at 800 nm. With an overall diameter of around 6.7 nm, the d-dots could gain access to the cell nucleus without any surface decoration, demonstrating their promising broad applications as fluorescent labels.
机译:掺杂的量子点(d点)可以用作生物应用的荧光生物传感器和生物标记。我们的研究描述了一种通过巯基丙酸(MPA)封端的Mn 2 + :ZnSe / ZnO d-点的合成方法,该方法简便易行,经济高效。所制备的水溶性d-点在约200℃下显示出强发射。 580 nm,具有高达31%的光致发光量子产率(PLQY),这是迄今为止通过水性途径制备的此类颗粒报道的最高值。它们在800 nm激发时也表现出上转换发射。 d点的总直径约为6.7 nm,可以在不进行任何表面修饰的情况下进入细胞核,这证明了它们作为荧光标记具有广阔的前景。

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