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Primate area V1: Largest response gain for receptive fields in the straight-ahead direction

机译:灵长类动物区V1:在直行方向上对接收场的最大响应增益

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摘要

Although neuronal responses in behaving monkeys are typically studied while the monkey fixates straight ahead, it is known that eye position modulates responses of visual neurons. The modulation has been found to enhance neuronal responses when the receptive field is placed in the straight-ahead position for neurons receiving input from the peripheral, but not the central retina []. We studied the effect of eye position on the responses of V1 complex cells receiving input from the central retina (1.1–5.7° eccentricity) while minimizing the effect of fixational eye movements. Contrast response functions were obtained separately with drifting light and dark bars. Data were fit with the Naka-Rushton equation: r(c) = Rmax ∗ cn/(cn + c50n) + s, where r(c) is mean spike rate at contrast c, Rmax the maximum response, c50 the contrast that elicits half of Rmax and s the spontaneous activity. Contrast sensitivity as measured by c50 was not affected by eye position. For dark bars there was a statistically significant decline in the normalized Rmax with increasing deviation from straight-ahead. Data for bright bars showed a similar trend with a less rapid decline. Our results indicate neurons representing the central retina show a bias for the straight-ahead position resulting from modulation of the response gain without an accompanying modulation of contrast sensitivity. The modulation is especially obvious for dark stimuli, which might be useful for directing attention to hazardous situations such as dark holes, or shadows concealing important objects (, ).
机译:尽管通常在猴子直行固定时研究行为猴子的神经元反应,但众所周知,眼睛的位置会调节视觉神经元的反应。当神经野接受周围神经而不是中央视网膜的输入时,将接受场置于向前的位置时,调制会增强神经元的反应[]。我们研究了眼睛位置对从中央视网膜(1.1-5.7°偏心距)接收输入的V1复杂细胞的反应的影响,同时最大程度地减少了固定眼动的影响。对比响应函数分别使用明暗条漂移获得。数据符合Naka-Rushton方程:r(c)= Rmax ∗ c n /(c n + c50 n )+ s ,其中r(c)是对比c的平均尖峰频率,Rmax是最大响应,c50是引起Rmax和 s 自发活动一半的对比。用 c50 测量的对比度灵敏度不受眼睛位置的影响。对于黑条,归一化的 Rmax 的统计显着下降是与直行的偏差增加。亮条数据显示出类似的趋势,下降速度较快。我们的结果表明,代表中央视网膜的神经元显示出由于响应增益的调制而没有伴随对比敏感度的调制而导致的直线向前位置的偏差。调制对于暗刺激尤其明显,这可能有助于将注意力引向危险情况,例如黑洞或隐藏重要物体的阴影(,)。

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