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Expression of androgen receptor in the brain of a sub-oscine bird with an elaborate courtship display

机译:精心设计的雄性亚卵亚蛋鸟大脑中雄激素受体的表达

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摘要

Sex steroids control vertebrate behavior by modulating neural circuits specialized for sex steroid sensitivity. In birds, receptors for androgens (AR) and estrogens (ERα) show conserved expression in neural circuits controlling copulatory and vocal behaviors. Male golden-collared manakins have become a model for evaluating hormonal control of complex physical courtship displays. These birds perform visually and acoustically elaborate displays involving considerable neuromuscular coordination. Androgens activate manakin courtship and AR are expressed widely in spinal circuits and peripheral muscles utilized in courtship. Using in situ hybridization, we report here the distributions of AR and ERα mRNA in the brains of golden-collared manakins. Overall patterns of AR and ERα mRNA expression resemble what has been observed in non-vocal learning species. Notably, however, we detected a large area of AR expression in the arcopallium, a forebrain region that contains a crucial premotor song nucleus in vocal learning species. These results support the idea that AR signaling both centrally and peripherally is responsible for the activation of male manakin courtship, and the arcopallium is likely a premotor site for AR-mediated displays
机译:性类固醇通过调节专门用于性类固醇敏感性的神经回路来控制脊椎动物的行为。在鸟类中,雄激素(AR)和雌激素(ERα)受体在控制交配和声音行为的神经回路中显示保守表达。雄性金领manakins已成为评估复杂的物理求爱显示的荷尔蒙控制的模型。这些鸟会在视觉和听觉上进行精美的展示,涉及大量的神经肌肉协调。雄激素激活manakin求爱,AR在求爱中所用的脊髓回路和周围肌肉中广泛表达。使用原位杂交,我们在这里报告了金领山柑脑中AR和ERαmRNA的分布。 AR和ERαmRNA表达的总体模式类似于在非语音学习物种中观察到的模式。但是,值得注意的是,我们在arcopallium中检测到大面积的AR表达,arcopallium是一个前脑区域,在声乐学习物种中包含至关重要的运动前歌曲核。这些结果支持以下观点:AR信号在中央和外周均负责激活男性manakin求爱,而artopallium可能是AR介导的显示器的运动前位点

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