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Scaffold-Based Delivery of Autologous Mesenchymal Stem Cells for Mandibular Distraction Osteogenesis: Preliminary Studies in a Porcine Model

机译：基于支架的自体间充质干细胞用于下颌骨成骨的递送：在猪模型中的初步研究

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PurposeBone regeneration through distraction osteogenesis (DO) is promising but remarkably slow. To accelerate it, autologous mesenchymal stem cells have been directly injected to the distraction site in a few recent studies. Compared to direct injection, a scaffold-based method can provide earlier cell delivery with potentially better controlled cell distribution and retention. This pilot project investigated a scaffold-based cell-delivery approach in a porcine mandibular DO model.

机译：目的通过分散成骨作用（DO）进行骨再生是有希望的，但速度非常慢。为了加速它，在最近的一些研究中已经将自体间充质干细胞直接注射到了分散部位。与直接注射相比，基于支架的方法可以提供更早的细胞递送，并可能更好地控制细胞的分布和保留。该试验项目研究了猪下颌DO模型中基于支架的细胞递送方法。

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期刊名称 other
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Zongyang Sun; Boon Ching Tee; Kelly S. Kennedy; Patrick M. Kennedy; Do-Gyoon Kim; Susan R. Mallery; Henry W. Fields;
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年(卷),期 -1(8),9
年度 -1
页码 e74672
总页数 14
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专利

1. Application of Autologous Human Bone Marrow-Derived Mesenchymal Stem Cells in Distraction Osteogenesis for the Treatment of Bilateral Mandibular Hypoplasia [J] . Lim Hun Jun, Lee Eui Mook, Kim Won Ki, The Journal of craniofacial surgery . 2018,第6期

机译：自体骨髓间充质干细胞在分散骨质发生中的施用中的应用
2. Bone regeneration by transplantation of human mesenchymal stromal cells in a rabbit mandibular distraction osteogenesis model [J] . KimI.S., ChoT.H., LeeZ.H., Tissue engineering, Part A . 2013,第1a2期

机译：人间充质基质细胞移植在兔下颌骨成骨模型中的骨再生
3. Addition of mesenchymal stem cells to the scaffold of platelet-rich plasma is beneficial for the reduction of the consolidation period in mandibular distraction osteogenesis. [J] . Hwang YJ, Choi JY Journal of Oral and Maxillofacial Surgery . 2010,第5期

机译：在富含血小板的血浆支架中添加间充质干细胞有利于减少下颌骨牵引成骨的巩固期。
4. Microfluidic co-culture system model to study the interplay between sensory neurons and mesenchymal stem cells: new clues towards osteogenesis [C] . Hugo Oliveira, Bruno P Dos Santos, Diana I Silva, World biomaterials congress . 2016

机译：微流体共培养系统模型，用于研究感觉神经元和间充质干细胞之间的相互作用：成骨的新线索
5. Local Delivery of Mesenchymal Stem Cells Expressing Osteogenesis-Inducing MicroRNA for Bone Tissue Engineering Applications [D] . Arriaga, Marco Antonio 2018

机译：表达成骨诱导性microRNA的间充质干细胞的局部递送，用于骨组织工程应用
6. Conditioned medium from mesenchymal stem cells improves condylar resorption induced by mandibular distraction osteogenesis in a rat model [O] . Wataru Katagiri, Satoshi Endo, Ryoko Takeuchi, 2021

机译：来自间充质干细胞的调节培养基改善了大鼠模型中下颌分散骨质发生诱导的髁突血清吸收
7. Scaffold-based delivery of autologous mesenchymal stem cells for mandibular distraction osteogenesis: preliminary studies in a porcine model. [O] . Zongyang Sun, Boon Ching Tee, Kelly S Kennedy, 2013

机译：基于支架的自体间充质干细胞递送用于下颌骨牵张成骨：在猪模型中的初步研究。

Scaffold-Based Delivery of Autologous Mesenchymal Stem Cells for Mandibular Distraction Osteogenesis: Preliminary Studies in a Porcine Model

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