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Reconstruction of normal and abnormal gastric electrical sources using a potential based inverse method

机译:使用基于电位的逆方法重建正常和异常胃电源

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摘要

The use of cutaneous recordings to non-invasively characterize gastric slow wave had limited clinical acceptance, primarily due to the uncertainty in relating the recorded signal to the underlying gastric slow waves. In this study we aim to distinguish and quantitatively reconstruct different slow wave patterns using an inverse algorithm. Slow wave patterns corresponding to normal, retrograde and uncoupled activity at different frequencies were imposed on a model of the stomach surface. Gaussian noise (10% peak-to-peak) was added to cutaneous potentials and the Greensite-Tikhonov inverse method was used to reconstruct the potentials on the stomach. The effectiveness of the number or location of electrodes on the accuracy of the inverse solutions was investigated using four different electrode configurations. Results showed the reconstructed solutions were able to reliably distinguish the different slow wave patterns and waves with lower frequency were better correlated to the known solution than those with higher. The use of up to 228 electrodes improved the accuracy of the inverse solutions. However, the use of 120 electrodes concentrated around the stomach was able to achieve similar results. The most efficient electrode configuration for our model involved 120 electrodes with an inter-electrode distance of 32 mm.
机译:主要由于归因于所记录的信号与潜在的胃慢波之间的不确定性,使用皮肤记录来非侵入性地表征胃慢波具有有限的临床接受度。在这项研究中,我们旨在使用逆算法来区分和定量重建不同的慢波模式。将对应于不同频率下正常,逆行和未耦合活动的慢波模式强加给胃表面模型。高斯噪声(峰峰值的10%)添加到皮肤电势,Greensite-Tikhonov逆方法用于重建胃电势。使用四种不同的电极配置研究了电极数量或位置对反解精度的影响。结果表明,重构后的解能够可靠地区分不同的慢波模式,并且频率较低的波与已知的解比具有较高频率的波具有更好的相关性。多达228个电极的使用提高了反解的精度。但是,使用120个集中在胃周围的电极可以达到类似的效果。对于我们的模型,最有效的电极配置包括120个电极,电极间距离为32 mm。

著录项

  • 期刊名称 other
  • 作者

    J HK Kim; P Du; L K Cheng;

  • 作者单位
  • 年(卷),期 -1(34),9
  • 年度 -1
  • 页码 1193–1206
  • 总页数 18
  • 原文格式 PDF
  • 正文语种
  • 中图分类
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