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ELASTICITY ESTIMATES FROM IMAGES OF CRAWLING WAVES GENERATED BY MINIATURE SURFACE SOURCES

机译:从微型表面源生成的爬行波图像估算弹性

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摘要

We present a surface-based approach to generate shear wave interference patterns, called crawling waves (CrW), within a medium and derive local estimates of biomechanical properties of tissue. In previous experiments, elongated bars operating as vibration sources were used to generate CrW propagation in samples. In the current study, however, a pair of miniature circular vibration sources is applied to the overlying skin to generate the CrW within the medium. The shape and position of the miniature sources make this configuration more applicable for in vivo implementation. A modified ultrasound imaging system is used to display the CrW propagation. A shear speed mapping algorithm is developed using a detailed analysis of the CrW. The proposed setup is applied to several biomaterials including a homogeneous phantom, an inhomogeneous phantom, and ex vivo human liver. The data are analyzed using the mapping algorithm to reveal the biomechanical properties of the biomaterials.
机译:我们提出了一种基于表面的方法来在介质内生成剪切波干涉图,称为爬行波(CrW),并得出组织的生物力学特性的局部估计值。在先前的实验中,使用细长杆作为振动源,以在样品中产生CrW传播。但是,在当前的研究中,将一对微型圆形振动源应用于上覆皮肤,以在介质中生成CrW。微型源的形状和位置使此配置更适用于体内实施。改进的超声成像系统用于显示CrW传播。使用CrW的详细分析开发了剪切速度映射算法。拟议的设置应用于几种生物材料,包括均质体模,不均质体模和离体人类肝脏。使用映射算法分析数据以揭示生物材料的生物力学特性。

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