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Age as a Risk Factor for Stroke in Atrial Fibrillation Patients: Implications in Thromboprophylaxis in the Era of Novel Oral Anticoagulants

机译:年龄是房颤患者中风的危险因素:新型口服抗凝剂时代血栓预防的意义

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摘要

Atrial fibrillation is associated with significant morbidity and mortality. There is a strong relationship between atrial fibrillation and aging, thromboembolism, stroke, congestive heart failure and hypertension. In addition, advanced age is a powerful risk factor for stroke and thromboembolism in patients with atrial fibrillation.For many years, vitamin K antagonists were the only approved anticoagulants for the management of atrial fibrillation. Lately new anticoagulants made their appearance and large trials have already shown their superiority against vitamin K antagonists. Since the arrhythmia is encountered frequently in the elderly, it is crucial to identify the beneficial effects of the novel oral anticoagulants in this particular patient population.
机译:心房纤颤与明显的发病率和死亡率有关。心房纤颤与衰老,血栓栓塞,中风,充血性心力衰竭和高血压之间存在密切关系。此外,高龄是房颤患者中风和血栓栓塞的重要危险因素。多年来,维生素K拮抗剂是唯一被批准用于治疗房颤的抗凝剂。最近出现了新的抗凝剂,大量试验已经显示出它们对维生素K拮抗剂的优越性。由于老年人心律失常频发,因此确定新型口服抗凝剂在该特定患者人群中的有益作用至关重要。

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