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Development and validation of a risk model for identification of non-neutropenic critically ill adult patients at high risk of invasive Candida infection: the Fungal Infection Risk Evaluation (FIRE) Study.

机译：开发和验证标识的非中性粒细胞减少危重成人患者的侵袭性念珠菌感染的高危风险模型：真菌感染风险评估（FIRE）研究。

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BACKGROUNDThere is increasing evidence that invasive fungal disease (IFD) is more likely to occur in non-neutropenic patients in critical care units. A number of randomised controlled trials (RCTs) have evaluated antifungal prophylaxis in non-neutropenic, critically ill patients, demonstrating a reduction in the risk of proven IFD and suggesting a reduction in mortality. It is necessary to establish a method to identify and target antifungal prophylaxis at those patients at highest risk of IFD, who stand to benefit most from any antifungal prophylaxis strategy.

机译：背景技术越来越多的证据表明，在重症监护病房的非中性粒细胞减少患者中，侵袭性真菌病（IFD）的发生可能性更高。许多随机对照试验（RCT）评估了非中性粒细胞减少症，重症患者的抗真菌药物预防效果，证明已证实的IFD风险降低，并提示死亡率降低。有必要建立一种方法来识别和预防那些有IFD最高风险的患者，这些患者将从任何抗真菌预防策略中受益最大。

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期刊名称 other
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D Harrison; H Muskett; S Harvey; R Grieve; J Shahin; K Patel; Z Sadique; E Allen; R Dybowski; M Jit; J Edgeworth; C Kibbler; R Barnes; N Soni; K Rowan;
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年(卷),期 -1(17),3
年度 -1
页码 1–156
总页数 7
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1. Development and validation of a risk model for identification of non-neutropenic, critically ill adult patients at high risk of invasive Candida infection: the Fungal Infection Risk Evaluation (FIRE) Study [J] . Health technology assessment: HTA . 2013,第3期

机译：风险模型的开发和验证，以鉴定具有高侵袭性念珠菌感染风险的非中性粒细胞减少症，重症成年患者：真菌感染风险评估（FIRE）研究
2. Risk factors for Candida colonization/infection in non-neutropenic medical critically ill patients [J] . J Nolla, C Leon, R JordaMA Leon, Critical care : . 2001,第Suppla1期

机译：非中性粒细胞减少症危重患者念珠菌定植/感染的危险因素
3. Risk factors for invasive candida infection in adult critically ill patients: a meta-analysis [J] . Bloos F., Schlattmann P., Pletz M., Infection . 2015,第Suppla1期

机译：成人危重病人侵袭性念珠菌感染的危险因素：一项荟萃分析
4. Influence of patient care with invasive devices on the risk of healthcare-associated infections [C] . Diana Platace, Ilze Klava, Lilija Antonevica, International Conference on Environmental, Industrial and Applied Microbiology . 2009

机译：患者护理对侵袭性装置对医疗相关感染风险的影响
5. Behavioral factors affecting risk for invasive fungal infections among transplant patients. [D] . Kriengkauykiat, Jane. 2015

机译：影响移植患者侵袭性真菌感染风险的行为因素。
6. Risk factors for Candida colonization/infection in non-neutropenic medical critically ill patients [O] . J Nolla, C León, R Jordá, 2001

机译：非中性粒细胞减少症危重患者念珠菌定植/感染的危险因素
7. Response to van Saene et al.'s comment on "Prevention of severe Candida infections in non-neutropenic, high-risk, critically ill patients" [O] . Thierry Calandra, Oscar Marchetti 2003

机译：对Van Saene等人的回应。评论“预防非中性，高风险，严重病人的严重念珠菌感染”

Development and validation of a risk model for identification of non-neutropenic critically ill adult patients at high risk of invasive Candida infection: the Fungal Infection Risk Evaluation (FIRE) Study.

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