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Testing Putative Causal Associations of Risk Factors for Early Intercourse in the Study of Twin Adults: Genes and Environment (STAGE)

机译：试验危险因子危险因子危险因子危险因素对双胞胎成人研究的早期性交：基因与环境（阶段）

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摘要

Adverse childhood experiences and substance use have been identified as potential causal risk factors for early-onset sexual intercourse. While it is possible that exposure to these risk factors directly increases the likelihood of engaging in early intercourse, an alternative explanation is that observed associations between these variables are due to shared familial confounds. These unmeasured confounds may increase the likelihood of being exposed to these risk factors and of engaging in early intercourse. Participants drawn from a population-based study of Swedish adult twins (ages 19–47 years; N = 12,126) reported on their history of exposure to early physical and sexual trauma, cigarette use, and cannabis use. We investigated the nature of the association between these risk factors and young age at first intercourse, using a comparison of twins differentially exposed to each risk factor. When compared to non-exposed, unrelated individuals, participants who reported adverse childhood experiences or who engaged in early cigarette use or cannabis use were more likely to engage in early intercourse. However, co-twin comparisons indicated that observed associations between these risk factors and early intercourse may be due to familial factors shared within twin pairs, and risk factor exposure may not lead directly to early intercourse. Our results suggest that preventing trauma exposure or preventing or delaying adolescents’ cigarette smoking or cannabis use may not effectively delay intercourse onset; instead, other aspects of the adolescent’s environment should be addressed.
机译：不利的童年经验和物质使用被认为是早期性交的潜在因果危险因素。虽然可能导致这些风险因素直接增加接合早期性交的可能性，但是另一种解释是观察到这些变量之间的关联是由于共同的家族困惑。这些未测量的混淆可能会增加暴露于这些危险因素的可能性以及从早期的性交接触。从基于人口的瑞典成人双胞胎研究（19-47岁; N = 12,126岁）的参与者报告了他们暴露于早期身体和性创伤，香烟用途和大麻使用的历史。我们在第一次性交时调查了这些风险因素和年轻时之间的关联性质，使用差异暴露于每个危险因素的双胞胎的比较。与非暴露的无关个人相比，报告童年经历或从事早期卷烟使用或大麻使用的参与者更有可能从事早期性交。然而，共同的比较表明，观察到这些风险因素和早期性交之间的关联可能是由于双对成对中共有的家族因素，并且风险因素暴露可能不会直接导致早期性交。我们的研究结果表明，防止创伤或预防或预防或延迟青少年吸烟或大麻使用可能不会有效地延迟交脑;相反，应该解决青少年环境的其他方面。

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