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Comparison of Role of Early (6 Hours) to Later (6 Hours) or No Cardiac Catheterization Following Resuscitation From Out-of-hospital Cardiac Arrest

机译:在从医院外心脏骤停的复苏后早期(6小时)至后期( 6小时)或没有心脏导管的比较

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摘要

Despite reports of patients with resuscitated sudden cardiac arrest (rSCA) receiving acute cardiac catheterization, the efficacy of this strategy is largely unknown. We hypothesized that acute cardiac catheterization of patients with rSCA would improve survival to hospital discharge. A retrospective cohort of 240 patients with out-of-hospital rSCA due to ventricular tachycardia or fibrillation was identified from 11 institutions in Seattle, Washington, between 1999 and 2002. Patients were grouped into those receiving acute catheterization within 6 hours (≤ 6 hours group, n = 61) and into those with deferred catheterization at > 6 hours or no catheterization during the index hospitalization (>6 hours group, n = 179). We directed attention to survival to hospital discharge, neurologic status, extent of coronary artery disease presenting electrocardiographic (ECG) findings, and pre-arrest symptoms. Propensity score methods were used to adjust for the likelihood of receiving acute catheterization. Survival was greater in patients who underwent acute catheterization ≤ 6 hours group (72%) vs. >6 hours group (49%) (p=0.001). Percutaneous coronary intervention was performed in 38/61 (62%) of patients in ≤ 6 hours group, and 13/170 (7%) in > 6 hours group, p<0.0001. Neurologic status was similar for both groups. A significantly higher percentage of patients in the acute catheterization group had symptoms prior to cardiac arrest, and had ST-segment elevation on post-resuscitation ECG. Age, bystander cardiopulmonary resuscitation, daytime presentation, history of percutaneous coronary intervention or stroke, and acute ST elevation were all positively associated with receiving cardiac catheterization. In conclusion, in this series of patients who sustained out-of-hospital cardiac arrest, acute catheterization (within 6 hours of presentation) was associated with improved survival.

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