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Transport of lipopolysaccharide across the cell envelope: the long road of discovery

机译：跨细胞膜脂多糖交通：发现的漫漫长路

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Intracellular lipid transport is poorly understood. Genetic studies to identify lipid-transport factors are complicated by the essentiality of many lipids, while biochemical and cell biology approaches aiming to determine localization and mechanisms of lipid transport are often challenged by the lack of adequate technology. Here we review the epic history of how different approaches, technological advances, and ingenuity contributed to the recent discovery of a multi-protein pathway that transports lipopolysaccharide across the envelope of Gram-negative bacteria.

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Natividad Ruiz; Daniel Kahne; Thomas J. Silhavy;
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年(卷),期 -1(7),9
年度 -1
页码 677–683
总页数 16
原文格式 PDF
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专利

1. Transport of lipopolysaccharides across the bacterial cell envelope [J] . Ruiz Natividad Glycobiology. . 2017,第12期

机译：脂多糖在细菌细胞包络上运输
2. A New Family of Membrane Electron Transporters and Its Substrates, Including a New Cell Envelope Peroxiredoxin, Reveal a Broadened Reductive Capacity of the Oxidative Bacterial Cell Envelope [J] . Seung-Hyun Cho, Derek Parsonage, Casey Thurston, MBio . 2012,第2期

机译：膜细胞电子转运蛋白及其底物的新家族，包括新的细胞包膜过氧化物酶，揭示了氧化细菌细胞包膜的还原能力增强
3. A20 Silencing by Lipid Envelope-Type Nanoparticles Enhances the Efficiency of Lipopolysaccharide-Activated Dendritic Cells [J] . Warashina S, Nakamura T, Harashima H Biological & pharmaceutical bulletin . 2011,第8期

机译：脂质包封型纳米粒子的A20沉默提高脂多糖激活的树突状细胞的效率。
4. Effect of lipopolysaccharides on hepatocellular transport processes [C] . S. GRUNE Falk Symposium . 2000

机译：脂多糖对肝细胞运输过程的影响
5. Lipopolysaccharide assembly in Escherichia coli. Part A: Characterization of the function and biogenesis of the two-protein complex involved in LPS assembly at the outer membrane. Part B: Reconstitution of LPS transport across the periplasm via a trans-envelope protein complex [D] . Chng, Shu Sin 2010

机译：大肠杆菌中的脂多糖组装体。 A部分：表征LPS组装在外膜上的两种蛋白质复合物的功能和生物发生。 B部分：通过跨包膜蛋白复合物重建脂多糖跨周质的运输
6. The Lack of the Essential LptC Protein in the Trans-Envelope Lipopolysaccharide Transport Machine Is Circumvented by Suppressor Mutations in LptF, an Inner Membrane Component of the Escherichia coli Transporter [O] . Mattia Benedet, Federica A. Falchi, Simone Puccio, 2011

机译：在跨信封脂多糖转运机中缺少必需的LptC蛋白是通过LptF（大肠杆菌转运蛋白的内膜成分）中的抑制子突变来避免的。
7. Roads to the Edge of the Cell: Intracellular Transport of Cornified Envelope Precursors [O] . Määttä Arto 2004

机译：通往细胞边缘的道路：角质化信封前体的细胞内运输。

Transport of lipopolysaccharide across the cell envelope: the long road of discovery

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