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Emotional memory function personality structure and psychopathology: A neural system approach to the identification of vulnerability markers

机译：情绪记忆功能人格结构和精神病理学：一种神经系统方法来识别脆弱性标记

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It is well established that emotional events are ingrained stronger into memory relative to neutral events. Facilitated emotional memory is highly variable between individuals within the normal population and is particularly exacerbated in those diagnosed with mood and anxiety disorders. In order to elucidate how variation of enhanced emotional memory within the normal population may manifest into psychopathological states, we explored the convergence between studies investigating the neural systems engaged in emotional memory facilitation and studies investigating how these systems differ from person to person. Converging evidence highlights the roles of three neural systems (1. Amygdala function and attention, 2. Neuroendocrine function, 3. Interactive effects with mood) that all govern emotional memory facilitation and are highly variable between individuals as a function of personality. We applied this neural system approach to models of vulnerability of three forms of psychopathology that are particularly characterized by atypical emotional memory function (depression, generalized anxiety disorder and post-traumatic stress disorder). This application suggests that the incorporation of known vulnerability markers across psychological, neuroimaging and neuroendocrinological domains is cardinal to how susceptibility is conceptualized and assessed in these disorders.
机译：众所周知，与中立事件相比，情感事件更容易根深蒂固。在正常人群中，个体之间的易化情绪记忆高度可变，在被诊断为情绪和焦虑症的个体中尤其容易恶化。为了阐明正常人群中增强的情绪记忆的变化如何表现为心理病理状态，我们探讨了研究参与情绪记忆促进的神经系统的研究与研究这些系统因人而异的研究之间的融合。越来越多的证据凸显了三个神经系统的作用（1.杏仁核功能和注意力； 2。神经内分泌功能； 3。与情绪的交互作用），它们都控制着情绪记忆的促进作用，并且在个体之间因人格的变化而高度可变。我们将这种神经系统方法应用于三种形式的精神病理学的脆弱性模型，这些形式的典型特征是非典型的情绪记忆功能（抑郁，全身性焦虑症和创伤后应激障碍）。该申请表明，跨心理学，神经影像学和神经内分泌学领域纳入已知的易损性标志对于这些概念中易感性的概念化和评估至关重要。

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