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Neurodistribution of Androgen Receptor Immunoreactivity in the Male Frog Rana esculenta

机译:雄性蛙蛙中雄激素受体免疫反应的神经分布

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摘要

Sexual behavior in vertebrates depends on the cyclic release of steroids and their binding to the brain receptors. Previously, we demonstrated the presence of specific binding of 3H-testosterone and staining with PG-21 in the brain of the adult male frog, Rana esculenta. Here, we report our further receptor characterization using an anti–androgen receptor antiserum, PG-21, and the androgen site of action in frog brain. Nuclei, which contained cells labeled for the androgen receptor (AR), were mainly identified in the olfactory bulbs, preoptic-septal region, infundibulum, amygdala, thalamus, tectum, torus semicircularis, and medulla. The neuroanatomical AR staining appears similar to that in other lower vertebrates.
机译:脊椎动物的性行为取决于类固醇的周期性释放及其与脑受体的结合。以前,我们证明了成年雄性蛙Rana esculenta的脑中存在 3 H-睾丸激素特异性结合并用PG-21染色。在这里,我们报告了使用抗雄激素受体抗血清PG-21和青蛙脑中雄激素作用位点的进一步受体表征。核中含有标记有雄激素受体(AR)的细胞,主要在嗅球,视前隔区,漏斗,杏仁核,丘脑,顶盖,半圆环和延髓中鉴定。神经解剖学AR染色看起来与其他低等脊椎动物相似。

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