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首页> 美国卫生研究院文献>Antioxidants >Sideritis Perfoliata (Subsp. Perfoliata) Nutritive Value and Its Potential Medicinal Properties
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Sideritis Perfoliata (Subsp. Perfoliata) Nutritive Value and Its Potential Medicinal Properties

机译：铁皮炎（Perspoliata）的营养价值及其潜在的药用特性

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摘要

L. subsp. is an endemic species of the Eastern Mediterranean region with several uses in traditional medicine. The present study aims to explore the unknown properties of investigating the nutritional content as well as the antioxidant, anticancer, antituberculosis, antiwrinkle, anti-acne, hyper/hypo-pigmentation and antibacterial activities. Mineral content, nutritional value, the composition and antioxidant properties of the essential oil, the antityrosinase, the antibacterial activity and anti-elastase potential of the extract, were evaluated. The antiproliferative activity of against cervical cancer (HeLa), human melanoma (UCT-Mel-1), human hepatocellular carcinoma (HepG2) and human epidermoid carcinoma (A431) was investigated. Cytotoxic effects on normal human keratinocyte (HaCat) and kidney epithelial (Vero) cell lines were also determined. exhibited high nutritional value of proteins and minerals (K, P, Mg, Fe, Zn, Cu). The most abundant components of the essential oil were found to be α-pinene, β-phelladrene, valeranone, β-pinene and sabinene. The ethanolic extract of displayed moderate antioxidant potential and antibacterial activity against Noteworthy elastase and moderate anticancer potential against the human liver cancer cell line (HepG2) was observed with IC values of 57.18 ± 3.22 μg/mL and 64.27 ± 2.04 μg/mL respectively. The noteworthy activity of could be due to the presence of flavonoids and phenols in the leaves, having high nutritional value. could potentially be useful to reduce the appearance of wrinkles and for the treatment of liver cancer. The moderate antibacterial, antioxidant and elastase activity of the plant can be linked to the traditional use of for the treatment of wounds and inflammation.
机译：L.亚种是东地中海地区的特有物种，在传统医学中有多种用途。本研究旨在探索研究营养成分以及抗氧化剂，抗癌剂，抗结核药，抗皱，抗痤疮，色素沉着过度和抗菌活性的未知特性。评估了提取物的矿物质含量，营养价值，精油的组成和抗氧化特性，抗酪氨酸酶，抗菌活性和抗弹性蛋白酶的潜力。研究了其对宫颈癌（HeLa），人黑素瘤（UCT-Mel-1），人肝细胞癌（HepG2）和人表皮样癌（A431）的抗增殖活性。还确定了对正常人角质形成细胞（HaCat）和肾上皮细胞（Vero）的细胞毒性作用。表现出高蛋白和矿物质（钾，磷，镁，铁，锌，铜）的营养价值。发现精油中最丰富的成分是α-pine烯，β-ph烯，缬草酮，β-pine烯和sa烯。观察到乙醇提取物对人肝癌细胞株（HepG2）表现出适度的抗氧化潜力和抗菌活性，对人肝癌细胞具有中等的抗癌潜力，IC值分别为57.18±3.22μg/ mL和64.27±2.04μg/ mL。值得注意的活性可能是由于叶片中存在类黄酮和酚，具有很高的营养价值。可能有助于减少皱纹的出现并用于治疗肝癌。植物适度的抗菌，抗氧化和弹性蛋白酶活性可与传统的伤口和炎症治疗用途联系在一起。

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