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Introduction to Big Data in Colorectal Surgery: Use of the Rochester Epidemiology Project for Clinical Research in Colon and Rectal Surgery

机译:大肠外科大数据介绍:罗切斯特流行病学项目在结肠和直肠外科临床研究中的应用

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摘要

The Rochester Epidemiology Project (REP), a longitudinal population-based database, is the largest epidemiologic database in the world. Originally established at Mayo Clinic in Rochester, Minnesota, the REP has been instrumental in defining the natural history of disease states and the impact of treatment in a well-defined population. In the United States, the REP has made important contributions to the colon and rectal literature, largely because healthcare is fragmented with no unique identifier to longitudinally follow-up with a patient throughout the system over his or her lifespan. Investigation with the REP has provided insight to the economic burden associated with inflammatory bowel disease, the benefit of screening for colorectal cancer, and the natural history of Mekel's and diverticular disease. In addition to practice changing research, the REP can be used as a model for future linkage systems in the United States.
机译:罗切斯特流行病学项目(REP)是一个基于人口的纵向数据库,是世界上最大的流行病学数据库。 REP最初成立于明尼苏达州罗切斯特市的梅奥诊所,在确定疾病状态的自然史以及治疗对明确人群的影响方面发挥了重要作用。在美国,REP为结肠和直肠文献做出了重要贡献,主要是因为医疗保健零散而没有唯一的标识符,可以在整个生命周期中对患者进行整个系统的纵向随访。与REP的调查提供了与炎症性肠病相关的经济负担,筛查结直肠癌的益处以及梅克尔和憩室病的自然病史的见解。除了改变研究实践之外,REP还可以用作美国未来链接系统的模型。

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