首页> 美国卫生研究院文献>Diabetes Metabolism Journal >Letter: Comparison of the Efficacy of Rosuvastatin Monotherapy 20 mg with Rosuvastatin 5 mg and Ezetimibe 10 mg Combination Therapy on Lipid Parameters in Patients with Type 2 Diabetes Mellitus (Diabetes Metab J 2019;43:582–9)
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Letter: Comparison of the Efficacy of Rosuvastatin Monotherapy 20 mg with Rosuvastatin 5 mg and Ezetimibe 10 mg Combination Therapy on Lipid Parameters in Patients with Type 2 Diabetes Mellitus (Diabetes Metab J 2019;43:582–9)

机译:信函:瑞舒伐他汀单药20 mg瑞舒伐他汀5 mg和依泽替米贝10 mg联合治疗对2型糖尿病患者血脂参数的疗效比较(Diabetes Metab J 2019; 43:582–9)

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摘要

Diabetes is a major global public health threat. The prevalence of diabetes among Korean adults aged 30 years and older was 13.7% (4.8 million) in 2013 to 2014 and 14.4% (5.02 million) in 2016 [ , ]. About half of the people with diabetes had comorbidities. In Korea, 55.3% of people with diabetes had hypertension and 34.9% had hypercholesterolemia [ ]. With improvements in the treatment of diabetes and its associated conditions including hypertension and dyslipidemia, the incidence of cardiovascular diseases (CVDs) and mortality gradually decreased over recent decades [ , ]. However, only 8.4% of people with diabetes had good control of glucose (glycosylated hemoglobin [HbA1c] <6.5%), blood pressure (BP <140/85 mm Hg), and lipid profiles (low density lipoprotein cholesterol [LDL-C] <100 mg/dL). A 68.4% of people with diabetes achieved BP <140/85 mm Hg and 44.2% achieved LDL-C <100 mg/dL [ ]. Moreover, the prevalence of subclinical coronary atherosclerosis is higher than expected, and this could affect coronary artery disease progression in asymptomatic diabetic patients [ ]. Therefore, much more comprehensive management of diabetes should be planned to reduce diabetes-related morbidity and mortality.
机译:糖尿病是全球主要的公共卫生威胁。 2013年至2014年,韩国30岁及以上成年人的糖尿病患病率为13.7%(480万),2016年为14.4%(502万)[,]。大约一半的糖尿病患者患有合并症。在韩国,55.3%的糖尿病患者患有高血压,34.9%的患者患有高胆固醇血症[]。随着糖尿病及其相关病症(包括高血压和血脂异常)的治疗方法的改进,近几十年来心血管疾病(CVD)的发生率和死亡率逐渐降低[,]。但是,只有8.4%的糖尿病患者对血糖(糖基化血红蛋白[HbA1c] <6.5%),血压(BP <140/85 mm Hg)和脂质谱(低密度脂蛋白胆固醇[LDL-C])的控制良好<100 mg / dL)。糖尿病患者中有68.4%的人BP <140/85 mm Hg,LDL-C <100 mg / dL [44.2%]。此外,亚临床冠状动脉粥样硬化的患病率高于预期,这可能会影响无症状糖尿病患者的冠状动脉疾病进展。因此,应该计划对糖尿病进行更全面的管理,以减少与糖尿病相关的发病率和死亡率。

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