• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>Healthcare >Use of Oral Prednisolone and a 3-Phase Bone Scintigraphy in Patients with Complex Regional Pain Syndrome Type I
【2h】

Use of Oral Prednisolone and a 3-Phase Bone Scintigraphy in Patients with Complex Regional Pain Syndrome Type I

机译：口服强的松龙和三相骨闪烁显像在I型复杂区域疼痛综合征患者中的应用

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

To compare the treatment effects of a high-dose and low-dose oral steroid regimen based on changes in the radioisotope uptake ratio (RUR) observed from three-phase bone scintigraphy (TPBS) in patients with complex regional pain syndrome type I (CRPS I), we retrospectively analyzed data of 34 patients with CRPS I from traumatic brain injury and stroke. Depending on the dose of steroid administered, patients were divided into high-dose ( = 14) and low-dose steroid groups ( = 20). We compared the severity scores, Kozin’s classification scores, and RUR observed from TPBS between the two groups. There were significant changes in the severity scores and Kozin’s classification between the baseline and 2 weeks from baseline ( < 0.05), however, there were no significant differences in terms of changes in the scores, classification, or the RUR observed from TPBS at 2 weeks from baseline ( > 0.05). There were no treatment-emergent adverse events (TEAEs) such as blood pressure elevation, impaired glycemic control, or gastrointestinal disturbances. Our results indicate that the efficacy profile of a low-dose oral steroid regimen is comparable to that of a high-dose regimen in alleviating symptoms in CRPS I patients. However, additional prospective, large-scale, multi-center studies are warranted to confirm our results.
机译：根据三期骨闪烁显像（TPBS）对I型复杂区域疼痛综合征（CRPS I）患者的放射性同位素摄取率（RUR）的变化，比较高剂量和低剂量口服类固醇疗法的治疗效果），我们回顾性分析了34例来自颅脑外伤和中风的CRPS I患者的数据。根据所用类固醇的剂量，将患者分为高剂量（= 14）和低剂量类固醇（= 20）组。我们比较了两组之间的严重性评分，Kozin分类评分和从TPBS观察到的RUR。在基线和距基线2周之间（<0.05），严重程度评分和Kozin分类存在显着变化（<0.05），但是在2周时从TPBS观察到的评分，分类或RUR变化无明显差异相对于基线（> 0.05）。没有紧急治疗事件（TEAE），例如血压升高，血糖控制受损或胃肠道不适。我们的结果表明，在缓解CRPS I患者症状时，低剂量口服类固醇方案的疗效与高剂量方案相当。但是，必须进行其他前瞻性，大规模，多中心研究以证实我们的结果。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号