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Low-cost fabrication of optical tissue phantoms for use in biomedical imaging

机译:用于生物医学成像的光学组织体模的低成本制造

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摘要

The rapid development of new optical imaging techniques is dependent on the availability of low-cost and easily reproducible standards for technique validation. This work describes a low-cost fabrication process of an agar gel-based phantom that may accurately simulate the optical properties of different human tissues at 532 and 630nm wavelengths. It was designed to match the optical properties of the brain, bladder wall, and lung tissues. These low-cost phantoms use agar powders dissolved in water as the bulk matrix. The latter is loaded with varying amounts of India ink, and aluminium oxide Al O particles for optical absorption and scattering targets. The optical properties (absorption and scattering coefficients), the primary design factor and critical parameters of these phantoms were deduced from measurements of the total attenuation coefficients .
机译:新的光学成像技术的迅速发展取决于用于技术验证的低成本且易于再现的标准。这项工作描述了一种基于琼脂凝胶的幻影的低成本制造工艺,该工艺可以准确地模拟532和630nm波长下不同人体组织的光学特性。它旨在与大脑,膀胱壁和肺组织的光学特性匹配。这些低成本的幻影使用溶解在水中的琼脂粉作为主体基质。后者装有各种量的印度墨水和氧化铝Al O颗粒,用于光学吸收和散射目标。这些体模的光学特性(吸收系数和散射系数),主要设计因子和关键参数是通过对总衰减系数的测量得出的。

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