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Corneal thickness measurement by secondary speckle tracking and image processing using machine-learning algorithms

机译:使用机器学习算法通过二次斑点跟踪和图像处理来测量角膜厚度

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摘要

Corneal thickness (CoT) is an important tool in the evaluation process for several disorders and in the assessment of intraocular pressure. We present a method enabling high-precision measurement of CoT based on secondary speckle tracking and processing of the information by machine-learning (ML) algorithms. The proposed configuration includes capturing by fast camera the laser beam speckle patterns backscattered from the corneal–scleral border, followed by ML processing of the image. The technique was tested on a series of phantoms having different thicknesses as well as in clinical trials on human eyes. The results show high accuracy in determination of eye CoT, and implementation is speedy in comparison with other known measurement methods.
机译:角膜厚度(CoT)是评估几种疾病的方法以及评估眼内压的重要工具。我们提出了一种基于次级斑点跟踪和基于机器学习(ML)算法对信息进行处理的CoT高精度测量方法。提议的配置包括通过快速相机捕获从角膜-巩膜边界向后散射的激光束斑点图案,然后对图像进行ML处理。该技术已在一系列具有不同厚度的体模上进行了测试,并在人眼上进行了临床试验。结果表明确定眼睛CoT的准确性很高,并且与其他已知的测量方法相比,实现速度很快。

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