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Nanostructured Organic/Hybrid Materials and Components in Miniaturized Optical and Chemical Sensors

机译:微型光学和化学传感器中的纳米结构有机/混合材料和组件

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摘要

In the last decade, biochemical sensors have brought a disruptive breakthrough in analytical chemistry and microbiology due the advent of technologically advanced systems conceived to respond to specific applications. From the design of a multitude of different detection modalities, several classes of sensor have been developed over the years. However, to date they have been hardly used in point-of-care or in-field applications, where cost and portability are of primary concern. In the present review we report on the use of nanostructured organic and hybrid compounds in optoelectronic, electrochemical and plasmonic components as constituting elements of miniaturized and easy-to-integrate biochemical sensors. We show how the targeted design, synthesis and nanostructuring of organic and hybrid materials have enabled enormous progress not only in terms of modulation and optimization of the sensor capabilities and performance when used as active materials, but also in the architecture of the detection schemes when used as structural/packing components. With a particular focus on optoelectronic, chemical and plasmonic components for sensing, we highlight that the new concept of having highly-integrated architectures through a system-engineering approach may enable the full expression of the potential of the sensing systems in real-setting applications in terms of fast-response, high sensitivity and multiplexity at low-cost and ease of portability.
机译:在过去的十年中,由于旨在响应特定应用的技术先进系统的出现,生化传感器在分析化学和微生物学方面带来了突破性的突破。通过设计多种不同的检测方式,多年来已开发出几类传感器。然而,迄今为止,它们几乎没有用于主要关注成本和便携性的现场护理或现场应用中。在本综述中,我们报告了在光电,电化学和等离激元组件中使用纳米结构的有机化合物和杂化化合物作为微型化且易于集成的生化传感器的组成元素。我们展示了针对目标的有机和杂化材料的设计,合成和纳米结构如何不仅在用作活性材料的传感器功能和性能的调制和优化方面,而且在使用时的检测方案的体系结构方面实现了巨大的进步作为结构/包装组件。我们特别关注用于传感的光电,化学和等离激元组件,我们强调通过系统工程方法具有高度集成的体系结构的新概念可以使传感系统在实际应用中的潜力得到充分表达。快速响应,高灵敏度和复用性,以及低成本和易于携带的术语。

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