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Vitamin and Mineral Supplementation Practices in Preterm Infants: A Survey of Australian and New Zealand Neonatal Intensive and Special Care Units

机译：早产婴儿的维生素和矿物质补充实践：对澳大利亚和新西兰新生儿重症监护和特殊监护病房的调查

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Preterm infants are at increased risk of micronutrient deficiencies as a result of low body stores, maternal deficiencies, and inadequate supplementations. The aim of this survey was to investigate current vitamin and mineral supplementation practices and compare these with published recommendations and available evidence on dosages and long-term outcomes of supplementations in preterm infants. In 2018, a two-part electronic survey was emailed to 50 Australasian Neonatal Dietitians Network (ANDiN) member and nonmember dietitians working in neonatal units in Australia and New Zealand. For inpatients, all units prescribed between 400 and 500 IU/day vitamin D, compared to a recommended intake range of 400–1000 IU/day. Two units prescribed 900–1000 IU/day at discharge. For iron, 83% of respondents prescribed within the recommended intake range of 2–3 mg/kg/day for inpatients. Up to 10% of units prescribed 6 mg/kg/day for inpatients and at discharge. More than one-third of units reported routine supplementations of other micronutrients, including calcium, phosphate, vitamin E, and folic acid. There was significant variation between neonatal units in vitamin and mineral supplementation practices, which may contribute to certain micronutrient intakes above or below recommended ranges for gestational ages or birth weights. The variations in practice are in part due to differences in recommended vitamin and mineral intakes between expert groups and a lack of evidence supporting the recommendations for supplementations.
机译：由于身体储存量低，孕产妇缺乏和补充不足，早产婴儿的微量营养素缺乏症风险增加。这项调查的目的是调查目前的维生素和矿物质补充做法，并将其与已发表的建议以及早产儿补充剂量和长期结果的现有证据进行比较。 2018年，通过两部分电子调查通过电子邮件发送给了50个在澳大利亚和新西兰的新生儿科工作的澳大利亚新生儿营养师网络（ANDiN）成员和非成员营养师。对于住院患者，所有单位规定的维生素D摄入量在400至500 IU /天之间，而建议的摄入量范围为400-1000 IU /天。有两个单位规定每天放电900-1000 IU。对于铁，83％的受访者在住院患者的建议摄入量范围为2-3 mg / kg / day内开处方。住院和出院时，每天最多开处方的6 mg / kg /单位的10％。超过三分之一的单位报告称常规补充了其他微量营养素，包括钙，磷酸盐，维生素E和叶酸。维生素和矿物质补充方法的新生儿单位之间存在显着差异，这可能导致某些微量营养素摄入量高于或低于胎龄或出生体重的建议范围。实践中的差异部分是由于专家组之间推荐的维生素和矿物质的摄入量不同以及缺乏支持补充建议的证据所致。

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