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Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval

机译：具有遗传支持的药物靶标被批准的可能性是两倍吗？关于药物机制的遗传支持对药物批准可能性影响的订正估计数

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期刊名称 PLoS Genetics
作者
Emily A. King; J. Wade Davis; Jacob F. Degner;
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作者单位

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年(卷),期 2019(15),12
年度 2019
页码 -1
总页数 20
原文格式 PDF
正文语种
中图分类遗传学;
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专利

1. Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval [J] . Emily A. King, J. Wade Davis, Jacob F. Degner PLoS Genetics . 2019,第12期

机译：具有遗传支持的药物靶标被批准的可能性是两倍吗？关于药物机制的遗传支持对药物批准可能性影响的订正估计数
2. Correlation of Pharmacogenetic Results with Patient Medication Regimens: A Pilot Study for Reporting Gene-Drug and Drug-Drug Interactions with Pharmacy Support [J] . Reynolds K. K., Weitendorf F., Linder M. W. The Journal of molecular diagnostics: JMD . 2014,第6期

机译：药物遗传学结果与患者用药方案的相关性：一项报告基因药物和药物与药物相互作用的初步研究
3. The support of human genetic evidence for approved drug indications [J] . Matthew R Nelson, Hannah Tipney, Jeffery L Painter, Nature Genetics . 2015,第8期

机译：人类遗传证据支持批准的药物适应症
4. Recognition of Drug-Target Interaction Patterns using Genetic Algorithm-optimized Bayesian-regularized Neural Networks and Support Vector Machines [C] . Michael Fernandez, Akinori Sarai, Shandar Ahmad IEEE International Conference on Systems, Man and Cybernetics . 2009

机译：使用遗传算法优化贝叶斯正规的神经网络和支持向量机的药物 - 目标交互模式识别药物 - 目标相互作用模式
5. Integration of Alzheimer's Disease Genetics, Myeloid Cell Genomics and Gene Regulatory Networks Reveals Novel Disease Mechanisms, Drug Targets and Candidate Therapeutics [D] . Novikova, Gloriia. 2021

机译：阿尔茨海默病遗传学，骨髓细胞基因组学和基因监管网络的整合揭示了新型疾病机制，药物目标和候选治疗方法
6. Clinical pharmacogenomics in action: design assessment and implementation of a novel pharmacogenetic panel supporting drug selection for diseases of the central nervous system (CNS) [O] . E. Bothos, E. Ntoumou, K. Kelaidoni, 2021

机译：临床药替昔甙中的作用：设计评估和实施一种支持中枢神经系统疾病的药物选择（CNS）的新药遗工面板
7. Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval [O] . Emily A. King, J. Wade Davis, Jacob F. Degner 2019

机译：药物靶标是遗传支持的两倍可能获得批准？修订了遗传支持对药物机制对药物批准概率影响的估计

Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval

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