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Field-Effect Transistor Biosensors for Biomedical Applications: Recent Advances and Future Prospects

机译：用于生物医学应用的场效应晶体管生物传感器：最新进展和未来展望

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摘要

During recent years, field-effect transistor biosensors (Bio-FET) for biomedical applications have experienced a robust development with evolutions in FET characteristics as well as modification of bio-receptor structures. This review initially provides contemplation on this progress by analyzing and summarizing remarkable studies on two aforementioned aspects. The former includes fabricating unprecedented nanostructures and employing novel materials for FET transducers whereas the latter primarily synthesizes compact molecules as bio-probes (antibody fragments and aptamers). Afterwards, a future perspective on research of FET-biosensors is also predicted depending on current situations as well as its great demand in clinical trials of disease diagnosis. From these points of view, FET-biosensors with infinite advantages are expected to continuously advance as one of the most promising tools for biomedical applications.

机译：近年来，随着FET特性的发展以及生物受体结构的改变，用于生物医学应用的场效应晶体管生物传感器（Bio-FET）经历了强劲的发展。本文通过对上述两个方面的杰出研究进行分析和总结，初步对这一进展进行了思考。前者包括制造史无前例的纳米结构并为FET换能器采用新颖的材料，而后者主要合成紧凑分子作为生物探针（抗体片段和适体）。此后，根据目前的情况及其在疾病诊断的临床试验中的巨大需求，还可以预测FET生物传感器的研究前景。从这些角度来看，具有无限优势的FET生物传感器有望作为生物医学应用中最有前途的工具之一而不断发展。

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期刊名称 Sensors (Basel Switzerland)
作者
Cao-An Vu; Wen-Yih Chen;
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年(卷),期 2019(19),19
年度 2019
页码 -1
总页数 22
原文格式 PDF
正文语种
中图分类
关键词
FET biosensor; biomedical application; nanotransducer; field-effect transistor; aptamer; antibody;

机译：FET生物传感器;生物医学应用;纳米传感器;场效应晶体管;适体;抗体;

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专利

1. Advances in organic transistor-based biosensors: From organic electrochemical transistors to electrolyte-gated organic field-effect transistors [J] . Kergoat L., Piro B., Berggren M., Analytical and bioanalytical chemistry . 2012,第5期

机译：基于有机晶体管的生物传感器的进展：从有机电化学晶体管到电解质门控有机场效应晶体管
2. Advances in organic transistor-based biosensors: from organic electrochemical transistors to electrolyte-gated organic field-effect transistors [J] . Loïg Kergoat, Benoît Piro, Magnus Berggren, Analytical and Bioanalytical Chemistry . 2012,第5期

机译：基于有机晶体管的生物传感器的进展：从有机电化学晶体管到电解质门控有机场效应晶体管
3. Graphene Field Effect Transistors for Biomedical Applications: Current Status and Future Prospects [J] . Rhiannan Forsyth, Anitha Devadoss, Owen J. Guy Diagnostics . 2017,第3期

机译：用于生物医学的石墨烯场效应晶体管：现状与未来展望
4. Low-noise high-speed Si nanowire field-effect transistors: Recent advances and opportunities in biosensor applications [C] . S. Vitusevich 2017 IEEE First Ukraine Conference on Electrical and Computer Engineering . 2017

机译：低噪声高速Si纳米线场效应晶体管：生物传感器应用的最新进展和机遇
5. Functionalization and Characterization of Nanomaterial Gated Field-Effect Transistor-Based Biosensors and the Design of a Multi-Analyte Implantable Biosensing Platform. [D] . Croce, Robert A., Jr. 2012

机译：纳米材料门控基于场效应晶体管的生物传感器的功能化和表征，以及多分析物可植入生物传感平台的设计。
6. Predicting Future Prospects of Aptamers in Field-Effect Transistor Biosensors [O] . Cao-An Vu, Wen-Yih Chen 2020

机译：预测场效应晶体管生物传感器中的适体的未来前景
7. Field-Effect Transistor Biosensors for Biomedical Applications: Recent Advances and Future Prospects [O] . 2019

机译：用于生物医学应用的现场效应晶体管生物传感器：最近的进展和未来的前景

Field-Effect Transistor Biosensors for Biomedical Applications: Recent Advances and Future Prospects

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